I 70 $east; US 40 $east, I 24 $east
957.2 mi15 hours 7 mins
| Head east on West Agnew Road | 9.0 mi | |
| Turn left onto North 56th Street (US 77) | 2.1 mi | |
| Continue onto South Chestnut Street (US 77) | 1.0 mi | |
| Turn right onto County Road A | 16.2 mi | |
| Turn left onto Highway 6 (US 6) | 0.9 mi | |
| Turn right onto South 255th Street | 0.5 mi | |
| Continue onto Ruff Road | 1.0 mi | |
| Turn left onto South 234th Street | 1.0 mi | |
| Make a slight right onto Pflug Road | 1,000 feet | |
| Make a slight left to stay on Pflug Road | 1.7 mi | |
| Turn left onto State Highway 31 (NE 31) | 1.0 mi | |
| Turn right onto Platteview Road | 11.1 mi | |
| Turn right to stay on Platteview Road | 5.1 mi | |
| Continue onto Hidden Valley Drive | 3.7 mi | |
| Continue onto US 34: Missouri River Bridge (US 34) | 4.1 mi | |
| Take the ramp | 0.6 mi | |
| Merge right onto I 29 S | 144.7 mi | |
| Keep left towards I 29 South: Kansas City | 14.6 mi | |
| Merge left onto I 29 S | 4.4 mi | |
| Keep left towards I 70 East: Saint Louis | 30.2 mi | |
| Continue onto I 70 E | 69.3 mi | |
| Keep left onto I 70 E | 142.4 mi | |
| Keep right onto I 70 E | 8.0 mi | |
| Take the ramp towards I 64 East: Louisville | 0.6 mi | |
| Merge left onto I 64 E | 70.1 mi | |
| Keep right towards I 57 South | 13.0 mi | |
| Continue onto I 57 S | 38.8 mi | |
| Take the ramp towards I 24 East: Nashville | 1.4 mi | |
| Continue onto I 24 E | 175.1 mi | |
| Keep right towards I 24 East: Nashville | 2.3 mi | |
| Keep left towards I 24 East: Chattanooga | 2.8 mi | |
| Keep right towards I 40 West: Memphis | 0.4 mi | |
| Merge left onto I 40 | 0.6 mi | |
| Keep left towards I 65 South: Huntsville | 0.4 mi | |
| Merge right onto I 65 S | 28.8 mi | |
| Keep left onto I-65 (I 65 S) | 66.1 mi | |
| Continue onto I 65 (I 65 S) | 0.2 mi | |
| Continue onto I-65 (I 65 S) | 43.4 mi | |
| Take exit 310 towards 157: Cullman | 0.3 mi | |
| Turn left onto University of North Alabama Highway (AL 157) | 500 feet | |
| Continue onto Section Line Road (AL 157) | 6.1 mi | |
| Turn left onto US 278 | 30.1 mi | |
| Turn right onto Murphree Valley Road | 1.2 mi | |
| Continue onto Murphee Valley Road | 1.0 mi | |
| Continue onto County Road 39 | 900 feet | |
| Turn left onto County Road 41 | 0.4 mi | |
| Continue onto County Highway 41 | 1.1 mi | |
| Make a sharp right onto Main Street (SR 132) | 100 feet | |
| You have arrived at your destination |
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Agnew, Nebraska - Altoona, Alabama