Avenue of the Saints, I 55 $south
698.1 mi11 hours 55 mins
| Head northwest on 220th Trail (IA 220) | 200 feet | |
| Make a sharp left onto W Avenue (US 151) | 2.9 mi | |
| Turn left onto US 6 | 11.7 mi | |
| Turn right onto Ireland Ave | 1.0 mi | |
| Take the ramp on the left | 0.4 mi | |
| Merge left onto I 80 | 0.7 mi | |
| Take the ramp towards US 218 South: Mount Pleasant | 0.7 mi | |
| Merge left onto Avenue of the Saints (US 218 S) | 140.1 mi | |
| Keep left towards US 61 South: Hannibal | 6.7 mi | |
| Continue onto McMasters Avenue (US 61 S) | 1.1 mi | |
| Continue onto Avenue of the Saints (US 61) | 0.7 mi | |
| Continue onto McMasters Avenue (US 61 S) | 1.6 mi | |
| Continue onto Avenue of the Saints (US 61 S) | 98.7 mi | |
| Take exit 25 towards I 270: Chicago | 0.3 mi | |
| Keep right towards I 270 South: Memphis | 0.3 mi | |
| Merge left onto I 270 S | 11.5 mi | |
| Take exit 1A towards I 55: Saint Louis | 0.4 mi | |
| Keep right towards I 55 South: Memphis | 0.4 mi | |
| Merge left onto I 55 S | 102.7 mi | |
| Keep left onto I 55 S | 76.1 mi | |
| Take the ramp on the left towards I 155 East: Caruthersville | 0.7 mi | |
| Merge right onto I 155 E | 25.7 mi | |
| Take the ramp towards US 51 South: Dyersburg | 43.1 mi | |
| Go straight onto Hollywood Drive (US 412 Business) | 1.7 mi | |
| Take the ramp on the right | 0.2 mi | |
| Merge left onto US 45 Bypass | 3.0 mi | |
| Turn right onto South Highland Avenue (US 45) | 38.4 mi | |
| Turn right onto Mulberry Avenue (US 45) | 16.4 mi | |
| Take the ramp onto MS 2 W | 0.3 mi | |
| Turn left onto US 72 | 58.3 mi | |
| Keep right towards Cullman | 36.8 mi | |
| Turn right onto South Danville Road | 4.1 mi | |
| Continue onto County Road 196 | 0.9 mi | |
| Continue slightly right onto County Road 195 | 2.1 mi | |
| Continue onto County Road 41 | 8.2 mi | |
| Turn left onto 1st Avenue (US 278) | 100 feet | |
| You have arrived at your destination |
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Amana, Iowa - Addison, Alabama