I 80, I 74 $east
589.1 mi9 hours 1 min
| Head east on West 1st Street | 1.3 mi | |
| Take the ramp on the right towards I-35 south: Des Moines | 0.4 mi | |
| Merge left onto I 35 S | 4.7 mi | |
| Take the ramp towards I 35 South: Kansas City | 1,000 feet | |
| Keep left towards I 80 East: Davenport | 0.8 mi | |
| Merge right onto I 80 | 284.0 mi | |
| Continue onto I 74 E | 7.5 mi | |
| Keep right towards I 55 South | 6.4 mi | |
| Keep left towards I 74 East: Indianapolis | 80.8 mi | |
| Take the ramp towards US 150 | 1,000 feet | |
| Keep left towards US 150 West | 1,000 feet | |
| Keep left towards I 74 East | 0.3 mi | |
| Merge left onto I 74 E | 85.4 mi | |
| Continue onto I 74 | 0.4 mi | |
| Continue onto I 74 E | 8.3 mi | |
| Take exit 53B towards I 65 South: Louisville | 0.5 mi | |
| Merge left onto I 65 S | 106.2 mi | |
| Take the ramp towards I 64: Lexington | 100 feet | |
| Keep right towards I 64 West: Saint Louis | 0.4 mi | |
| Merge right onto I 64 W | 0.8 mi | |
| Take the ramp towards 9th Street | 0.5 mi | |
| Keep right at the fork | 300 feet | |
| Go straight onto West Jefferson Street | 300 feet | |
| You have arrived at your destination |
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Ankeny, Iowa - Louisville, Kentucky