I 24 $east, I 75 $south
1,396.4 mi21 hours 26 mins
| Head east on West 1st Street | 1.3 mi | |
| Take the ramp on the right towards I-35 south: Des Moines | 0.4 mi | |
| Merge left onto I 35 S | 4.7 mi | |
| Take the ramp towards I 35 South: Kansas City | 1,000 feet | |
| Keep left towards I 80 East: Davenport | 0.8 mi | |
| Merge right onto I 80 | 2.5 mi | |
| Take the ramp towards US 65 South: Altoona | 0.7 mi | |
| Continue onto US 65 | 3.9 mi | |
| Take the ramp towards IA 163: Pleasant Hill | 0.4 mi | |
| Turn left onto East University Avenue (IA 163) | 3.3 mi | |
| Continue onto Northeast University Avenue (IA 163) | 1.8 mi | |
| Continue onto East University Avenue (IA 163) | 125.3 mi | |
| Merge left onto Avenue of the Saints (US 34 E) | 88.8 mi | |
| Keep left towards US 61 South: Hannibal | 6.7 mi | |
| Continue onto McMasters Avenue (US 61 S) | 1.1 mi | |
| Continue onto Avenue of the Saints (US 61) | 0.7 mi | |
| Continue onto McMasters Avenue (US 61 S) | 1.6 mi | |
| Continue onto Avenue of the Saints (US 61 S) | 73.8 mi | |
| Take the ramp on the left towards I 70 East: Saint Louis | 0.5 mi | |
| Merge left onto I 70 E | 12.3 mi | |
| Keep left onto I 70 E | 20.7 mi | |
| Keep right onto I 70 E | 8.0 mi | |
| Take the ramp towards I 64 East: Louisville | 0.6 mi | |
| Merge left onto I 64 E | 70.1 mi | |
| Keep right towards I 57 South | 13.0 mi | |
| Continue onto I 57 S | 38.8 mi | |
| Take the ramp towards I 24 East: Nashville | 1.4 mi | |
| Continue onto I 24 E | 175.1 mi | |
| Keep right towards I 24 East: Nashville | 2.3 mi | |
| Keep left towards I 24 East: Chattanooga | 2.8 mi | |
| Keep left towards I 40 East: Knoxville | 2.1 mi | |
| Keep right towards I 24 East: Chattanooga | 0.8 mi | |
| Keep left onto I 24 E | 133.0 mi | |
| Keep right towards Atlanta | 0.4 mi | |
| Merge left onto I 75 S | 111.0 mi | |
| Continue onto James Wendell George Parkway (I 75 S) | 2.3 mi | |
| Keep left onto I 75 S | 64.9 mi | |
| Take the ramp towards I 475 South: Valdosta | 15.6 mi | |
| Keep left towards I 75 South: Valdosta | 0.6 mi | |
| Merge left onto I 75 S | 300.1 mi | |
| Keep left towards South Turnpike | 42.1 mi | |
| Keep left onto Florida's Turnpike | 11.6 mi | |
| Take the ramp towards FL 528 Toll: International Airport | 0.4 mi | |
| Keep left at the fork | 1.2 mi | |
| Merge left onto Beachline Expressway (FL 528 Toll E) | 40.7 mi | |
| Take the ramp towards US 1: Cocoa | 0.2 mi | |
| Turn left onto Cocoa Boulevard (US 1) | 3.3 mi | |
| Turn left onto King Street (FL 520) | 0.7 mi | |
| Continue onto Hubert Humphrey Causeway (FL 520) | 0.8 mi | |
| Continue onto West Merritt Island Causeway (FL 520) | 0.6 mi | |
| Continue onto East Merritt Island Causeway (FL 520) | 0.9 mi | |
| You have arrived at your destination |
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Ankeny, Iowa - Merritt Island, Florida