I 85 $north, I 20
349.9 mi5 hours 33 mins
| Head north on North College Street | 300 feet | |
| Turn right onto East Glenn Avenue | 1.1 mi | |
| Keep right onto East Glenn Avenue | 0.2 mi | |
| Keep left onto East Glenn Avenue | 2.1 mi | |
| Make a slight right | 400 feet | |
| Go straight onto Bent Creek Road | 0.3 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 85 N | 90.9 mi | |
| Take the ramp towards I 285: Atlanta Bypass | 0.4 mi | |
| Keep right towards I 285 East: International Macon | 0.9 mi | |
| Merge left onto Perimeter (I 285 S) | 15.8 mi | |
| Take the ramp towards I 20 East: Augusta | 1.5 mi | |
| Keep left at the fork | 0.3 mi | |
| Merge left onto I 20 | 164.9 mi | |
| Take the ramp towards SC 39: Wagener | 0.3 mi | |
| Keep right towards SC 39: Wagener | 200 feet | |
| Go straight onto Old Ninety Six Indian Trail (SC 39) | 11.6 mi | |
| Continue onto Railroad Street West (SC 39) | 0.6 mi | |
| Continue onto Railroad Avenue East (SC 39) | 0.5 mi | |
| Continue onto Festival Trail Road (SC 39) | 2.3 mi | |
| Keep left onto Walker Street (SC 389) | 1.1 mi | |
| Continue onto John Nunn Highway (SC 389) | 4.1 mi | |
| Turn left onto Salley Road (SC 394) | 8.2 mi | |
| Turn right onto North Road (US 178) | 16.0 mi | |
| Continue onto Chestnut Street Northeast (US 178) | 3.4 mi | |
| Continue onto Whittaker Parkway (US 21) | 1.1 mi | |
| Turn left onto Five Chop Road (US 301) | 20.0 mi | |
| Turn left onto Bass Drive | 2.0 mi | |
| You have arrived at your destination |
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Auburn, Alabama - Santee, South Carolina