I 35 $south, US 69 $south
639.3 mi10 hours 14 mins
| Head east on Main Street (WI 133) | 800 feet | |
| Continue onto State Highway 133 (WI 133) | 6.7 mi | |
| Continue onto State Highway 130 (WI 130) | 2.2 mi | |
| Make a slight right to stay on State Highway 130 (WI 130) | 8.7 mi | |
| Turn right onto State Highway 23 (WI 23) | 5.4 mi | |
| Continue onto North Bequette Street (WI 23) | 0.8 mi | |
| Continue onto State Highway 23 (WI 23) | 0.2 mi | |
| Continue onto North Iowa Street (WI 23) | 0.2 mi | |
| Continue onto State Highway 23 (WI 23) | 600 feet | |
| Continue onto South Iowa Street (WI 23) | 0.2 mi | |
| Continue onto State Highway 23 (WI 23) | 1.0 mi | |
| Keep right towards US 151 South: Mineral Point | 0.2 mi | |
| Merge left onto US Highway 151 (US 151) | 36.4 mi | |
| Continue onto Great River Road (US 61) | 7.7 mi | |
| Continue onto Dubuque-Wisconsin Bridge (US 61 S) | 8.2 mi | |
| Take the ramp onto US 151 S | 56.9 mi | |
| Turn left onto US 151 S | 7.5 mi | |
| Keep right onto US 151 S | 6.8 mi | |
| Take the ramp towards I 380 South: Iowa City | 0.3 mi | |
| Merge left onto I 380 S | 0.3 mi | |
| Continue onto I 380 S | 15.6 mi | |
| Take the ramp towards I 80 West: Des Moines | 0.6 mi | |
| Merge left onto I 80 | 252.7 mi | |
| Continue onto I 35 S | 34.5 mi | |
| Keep left onto Chicago-Kansas City Expressway (I 35 S) | 1.5 mi | |
| Take exit 12 towards I 435 South: Saint Louis | 0.7 mi | |
| Merge left onto I 435 | 9.6 mi | |
| Keep left onto Lamar Hunt Memorial Highway (I 435) | 16.5 mi | |
| Take exit 79 towards Metcalf Avenue | 0.2 mi | |
| Turn left onto Metcalf Avenue | 1.3 mi | |
| Go straight onto Blue Valley Parkway | 0.7 mi | |
| Continue towards US 69 South: Fort Scott | 800 feet | |
| Take the ramp towards US 69 South: Fort Scott | 0.7 mi | |
| Merge left onto US 69 S | 102.4 mi | |
| Continue onto North Broadway Street (US 69 Business) | 4.1 mi | |
| Turn right onto West Centennial Drive (US 69 Business) | 500 feet | |
| Turn left onto US 69 S | 3.0 mi | |
| Turn right onto US 400 W | 30.7 mi | |
| Go straight | 0.3 mi | |
| Turn left onto Osborne Road (US 59) | 0.9 mi | |
| Continue onto North 16th Street (US 59) | 11.3 mi | |
| Turn right onto 14000 Road (US 160) | 0.6 mi | |
| Continue onto East 4th Street (US 160) | 0.9 mi | |
| You have arrived at your destination |
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Avoca, Wisconsin - Altamont, Kansas