Indiana Toll Road, Ohio Turnpike
1,230.4 mi19 hours 37 mins
| Head east on Main Street (WI 133) | 800 feet | |
| Continue onto State Highway 133 (WI 133) | 6.7 mi | |
| Continue onto State Highway 130 (WI 130) | 2.2 mi | |
| Make a slight right to stay on State Highway 130 (WI 130) | 8.7 mi | |
| Turn right onto State Highway 23 (WI 23) | 5.4 mi | |
| Continue onto North Bequette Street (WI 23) | 0.2 mi | |
| Turn left onto US 18 | 1.0 mi | |
| Enter the roundabout and take the 2nd exit onto US 18 | 100 feet | |
| Exit the roundabout onto US 18 | 0.3 mi | |
| Keep left onto US 18 | 36.5 mi | |
| Turn right onto McKee Road (CTH PD) | 0.9 mi | |
| Turn left onto South Seminole Highway | 1.5 mi | |
| Turn right onto West Beltline Frontage Road | 600 feet | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto West Beltline Highway (US 12) | 7.7 mi | |
| Take exit 267A towards I 39 South: Janesville | 0.8 mi | |
| Merge left towards I 39:I 90: Chicago | 82.5 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90) | 40.5 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90 E) | 1.0 mi | |
| Merge right onto Kennedy Expressway (I 90) | 5.6 mi | |
| Keep right onto Kennedy Expressway (I 90) | 8.3 mi | |
| Continue onto Dan Ryan Expressway (I 90) | 2.4 mi | |
| Keep left towards I 90 Express | 3.8 mi | |
| Take the ramp towards I 90 East: Chicago Skyway | 0.4 mi | |
| Merge right onto Dan Ryan Expressway (I 90) | 0.5 mi | |
| Keep left towards I 90 East: Chicago Skyway | 10.6 mi | |
| Keep left onto Indiana Toll Road (I 90) | 153.6 mi | |
| Continue onto Ohio Turnpike (I 80 E) | 141.5 mi | |
| Keep left onto Ohio Turnpike (I 80 E) | 9.2 mi | |
| Keep right onto I 480 E | 26.3 mi | |
| Keep right onto Outerbelt South Freeway (I 480 E) | 2.5 mi | |
| Merge left onto Outerbelt East Freeway (I 271 S) | 3.0 mi | |
| Keep right towards I 480: Youngstown | 10.6 mi | |
| Take the ramp towards Youngstown | 0.5 mi | |
| Keep right towards Youngstown | 1,000 feet | |
| Merge left onto Ohio Turnpike (I 80 E) | 53.8 mi | |
| Continue onto Pennsylvania Turnpike (I 76 E) | 1.2 mi | |
| Keep left towards E-ZPass Express | 29.6 mi | |
| Keep right onto Pennsylvania Turnpike (I 76 E) | 130.8 mi | |
| Take the ramp towards US 30: Breezewood | 1.9 mi | |
| Keep left towards US 30 West: Breezewood | 0.7 mi | |
| Turn left towards I 70 East: Baltimore | 75.9 mi | |
| Take the ramp towards Washington | 0.4 mi | |
| Continue onto Eisenhower Memorial Highway (I 270 N) | 22.9 mi | |
| Keep right onto I 270 S | 0.3 mi | |
| Continue onto I 270 N | 6.4 mi | |
| Keep right towards I 270 Spur: Washington | 2.0 mi | |
| Merge right onto Capital Beltway (I 495 W) | 1.2 mi | |
| Keep left onto Capital Beltway (I 495 W) | 4.7 mi | |
| Keep right onto Capital Beltway (I 495 S) | 11.3 mi | |
| Take the ramp towards I 95 South: Richmond | 0.5 mi | |
| Keep left at the fork | 0.3 mi | |
| Keep left towards I 95 South: Richmond | 0.4 mi | |
| Merge left onto Henry G. Shirley Memorial Highway (I 395 S) | 58.7 mi | |
| Continue onto I 95 S | 25.7 mi | |
| Take the ramp on the left towards I 295 South: Rocky Mount NC | 1.8 mi | |
| Merge right onto I 295 | 13.1 mi | |
| Take the ramp towards I 64 East: Norfolk | 1.2 mi | |
| Merge left onto I 64 E | 75.1 mi | |
| Keep right onto Hampton Roads Beltway (I 64 E) | 15.3 mi | |
| Take the ramp towards US 17 South: Elizabeth City | 0.4 mi | |
| Continue onto Chesapeake Expressway (VA 168) | 14.4 mi | |
| Continue onto South Battlefield Boulevard (VA 168) | 1.8 mi | |
| Continue onto Caratoke Highway (NC 168) | 43.0 mi | |
| Continue onto Wright Memorial Bridge (US 158) | 2.8 mi | |
| Continue onto North Croatan Highway (US 158) | 16.4 mi | |
| Make a slight left onto Cape Hatteras National Park Road | 8.3 mi | |
| Keep right onto NC 12 | 32.3 mi | |
| You have arrived at your destination |
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Avoca, Wisconsin - Avon, North Carolina