US 31, I 75 $south
505.9 mi8 hours 23 mins
| Head east on West Front Street | 900 feet | |
| Turn right onto Red Bud Trail South | 1.6 mi | |
| Turn left onto Pulaski Highway (US 12) | 2.0 mi | |
| Take the ramp | 0.4 mi | |
| Merge left onto Saint Joseph Valley Parkway (US 31 S) | 14.7 mi | |
| Take the ramp towards US 31 South: Plymouth | 111.7 mi | |
| Turn right onto East 216th Street | 0.5 mi | |
| Turn left onto Dunbar Road | 1,000 feet | |
| Turn left onto Sheridan Avenue (SR 38) | 7.0 mi | |
| Turn left onto Westfield Road (SR 32) | 800 feet | |
| Continue onto Conner Street (SR 32) | 0.4 mi | |
| Turn right onto South 8th Street | 0.7 mi | |
| Turn left onto Christian Avenue | 600 feet | |
| Enter the roundabout and take the 2nd exit onto Greenfield Avenue | 100 feet | |
| Exit the roundabout onto Greenfield Avenue | 1.2 mi | |
| Turn right onto SR 37 | 9.2 mi | |
| Take exit 200 towards I-465 | 0.2 mi | |
| Keep left towards I-465 South | 1.0 mi | |
| Merge left onto I 465 E | 7.9 mi | |
| Continue onto I 465 S | 1.3 mi | |
| Continue onto Interstate 465 (I 465 S) | 0.7 mi | |
| Continue onto I 465 S | 1.2 mi | |
| Take exit 49 towards I 74 East: Cincinnati | 700 feet | |
| Keep left towards I 74 East: Cincinnati | 70.4 mi | |
| Take exit 164 towards SR 1: Saint Leon | 0.2 mi | |
| Turn right onto SR 1 | 14.2 mi | |
| Turn right to stay on SR 1 | 600 feet | |
| Turn left onto Belleview Drive (SR 1) | 0.3 mi | |
| Continue towards I 275: Ohio | 0.4 mi | |
| Keep right towards I 275 South: Kentucky | 0.5 mi | |
| Merge left onto I 275 S | 0.6 mi | |
| Continue onto Carroll Lee Cropper Bridge (I 275 E) | 13.5 mi | |
| Take exit 84 towards I 71: Cincinnati | 0.3 mi | |
| Keep right towards I 71 South: Lexington | 0.7 mi | |
| Keep left towards I 71 South: Lexington | 0.3 mi | |
| Keep left at the fork | 0.7 mi | |
| Merge left onto I 71 S | 237.1 mi | |
| Continue onto I 275 S | 2.9 mi | |
| Keep right towards I 40 East: Asheville | 0.3 mi | |
| Keep right at the fork | 600 feet | |
| Keep left at the fork | 0.5 mi | |
| Go straight onto Henley Street (US 11) | 0.2 mi | |
| You have arrived at your destination |
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Buchanan, Michigan - Knoxville, Tennessee