I 75 $north, I 95 $north
393.8 mi6 hours 12 mins
| Head north on Main Street (US 301) | 0.3 mi | |
| Turn left onto West Belt Avenue (FL 48) | 1.7 mi | |
| Keep right onto FL 48 | 600 feet | |
| Take the ramp on the right | 100 feet | |
| Turn right | 0.3 mi | |
| Merge left onto I 75 N | 42.9 mi | |
| Take the ramp towards FL 326 | 0.2 mi | |
| Make a slight right | 100 feet | |
| Merge left onto FL 326 | 2.6 mi | |
| Turn left onto US 301 | 5.5 mi | |
| Keep right towards North US 301: Starke | 48.4 mi | |
| Go straight onto US 301 | 21.7 mi | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto I 10 E | 12.6 mi | |
| Take the ramp towards I-295: Daytona Beach | 0.2 mi | |
| Keep left towards I-295: Daytona Beach | 0.6 mi | |
| Merge left onto I 295 N | 14.2 mi | |
| Take the ramp on the left towards I 95 North: International Airport | 0.5 mi | |
| Merge left onto I 95 N | 164.9 mi | |
| Keep left towards I 95 North: Florence | 53.1 mi | |
| Take the ramp towards I 26 West: Columbia | 0.4 mi | |
| Merge left onto I 26 W | 14.4 mi | |
| Take the ramp towards US 301 South: Orangeburg | 0.3 mi | |
| Merge left onto Five Chop Road (US 301) | 6.6 mi | |
| Turn left onto John C Calhoun Drive (US 301) | 1.8 mi | |
| Turn right onto Broughton Street (US 178 Business) | 0.2 mi | |
| Turn right onto Russell Street (SC 33) | 300 feet | |
| You have arrived at your destination |
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Bushnell, Florida - Orangeburg, South Carolina