I 26 $west, I 95 $north
417.9 mi7 hours 23 mins
| Head north on Meeting Street (S-10-107) | 2.1 mi | |
| Take the ramp on the left | 0.4 mi | |
| Merge left onto I 26 W | 50.8 mi | |
| Take the ramp towards I 95 North: Florence | 0.8 mi | |
| Merge left onto I 95 N | 78.0 mi | |
| Take the ramp towards US 52: Florence | 800 feet | |
| Keep right at the fork | 600 feet | |
| Merge left onto West Lucas Street (US 52) | 1.5 mi | |
| Continue onto South Main Street (US 52) | 3.4 mi | |
| Continue straight to stay on South Main Street (US 52 Business) | 1.6 mi | |
| Turn right onto Pearl Street (SC 34) | 200 feet | |
| Turn left onto Exchange Street (SC 34) | 200 feet | |
| Turn right onto Cashua Street (SC 34) | 0.9 mi | |
| Turn left onto Society Hill Road | 13.4 mi | |
| Keep right onto Church Street | 1.0 mi | |
| Make a slight right onto Cheraw Highway (US 52) | 13.5 mi | |
| Merge left onto Market Street (US 1) | 0.9 mi | |
| Turn left onto 2nd Street (US 1) | 0.4 mi | |
| Turn right onto US 1 | 1.9 mi | |
| Turn left onto US 1 | 17.3 mi | |
| Keep left onto US 220 | 79.3 mi | |
| Take the ramp towards I 85 Business North: Burlington | 0.3 mi | |
| Merge left onto US 29 N | 3.4 mi | |
| Keep right towards US 29 North: Reidsville | 40.1 mi | |
| Take the ramp towards US 29 North | 0.7 mi | |
| Merge left onto Danville Expressway (US 29) | 58.2 mi | |
| Keep left onto Wards Road (US 29) | 9.2 mi | |
| Take the ramp on the right towards US 29 North | 0.6 mi | |
| Merge left onto Jerry Falwell Parkway (US 29) | 6.0 mi | |
| Continue towards US 460 East: Appomattox | 16.1 mi | |
| Take the ramp towards VA 24 East: To Route 60 | 0.3 mi | |
| Continue onto Old Courthouse Road (VA 24) | 10.0 mi | |
| Continue onto Mount Rush Highway (SR 24) | 1.1 mi | |
| Turn left onto Tower Hill Road | 4.4 mi | |
| You have arrived at your destination |
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Charleston, South Carolina - Virginia