How to get from Chicago, Illinois to Buffalo, New York

Discover, print or download the driving directions for the best route to go from Chicago, Illinois to Buffalo, New York.

Enlarge the route map Chicago, Illinois - Buffalo, New York

Driving directions from Chicago, Illinois to Buffalo, New York

Indiana Toll Road, Ohio Turnpike

533.6 mi8 hours 17 mins

Head north on North LaSalle Street 100 feet
Turn left onto West Randolph Street 0.7 mi
Take the ramp on the left towards I 90 East 900 feet
Merge right onto Kennedy Expressway (I 90) 0.5 mi
Continue onto Dan Ryan Expressway (I 90) 2.4 mi
Keep left towards I 90 Express 3.8 mi
Take the ramp towards I 90 East: Chicago Skyway 0.4 mi
Merge right onto Dan Ryan Expressway (I 90) 0.5 mi
Keep left towards I 90 East: Chicago Skyway 10.6 mi
Keep left onto Indiana Toll Road (I 90) 153.6 mi
Continue onto Ohio Turnpike (I 80 E) 141.5 mi
Keep left onto Ohio Turnpike (I 80 E) 9.2 mi
Keep right onto I 480 E 9.8 mi
Take the ramp towards I 71: Cleveland 0.7 mi
Keep left at the fork 0.3 mi
Merge left onto Berea Freeway 0.5 mi
Merge right onto I 71 N 8.5 mi
Merge left onto Innerbelt (I 90) 3.9 mi
Merge right onto Cleveland Memorial Shoreway (I 90) 1.5 mi
Continue onto Lakeland Freeway (I 90) 8.9 mi
Keep right towards I 90 East: Erie Pennsylvania 164.4 mi
Take exit 57 towards NY 75: Hamburg 0.8 mi
Keep right at the fork 0.2 mi
Go straight onto Camp Road (NY 75) 1.8 mi
Go straight onto Saint Francis Drive (NY 75) 1.0 mi
Continue onto State Highway 5 (NY 5) 1.1 mi
Continue onto Lake Shore Road (NY 5) 0.7 mi
Continue onto Hamburg Turnpike (NY 5) 1.2 mi
Continue onto Buffalo Skyway (NY 5) 4.7 mi
Continue onto Delaware Avenue (NY 384) 700 feet
You have arrived at your destination

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Chicago, Illinois - Buffalo, New York

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