US 36 $east; MO 110, US 63 $north
92.5 mi1 hour 40 mins
| Head south on North Washington Street (US 65 S) | 1.2 mi | |
| Take the ramp on the left towards US 36 East: Brookfield | 1,000 feet | |
| Merge left onto US 36 E | 58.0 mi | |
| Take the ramp towards US 63: Macon | 900 feet | |
| Turn left onto North Missouri Street (US 63) | 28.6 mi | |
| Take the ramp towards US 63 Business: Kirksville | 0.6 mi | |
| Continue onto South Baltimore Street (US 63 Bus) | 1.6 mi | |
| Keep left onto South Baltimore Street (US 63 Bus) | 2.1 mi | |
| You have arrived at your destination |
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Chillicothe, Missouri - Kirksville, Missouri