Harbor Tunnel Thruway, John F. Kennedy Memorial Highway
77.9 mi1 hour 21 mins
| Head south on Twin Rivers Road | 400 feet | |
| Turn left onto Governor Warfield Parkway | 0.6 mi | |
| Go straight onto Little Patuxent Parkway | 0.5 mi | |
| Continue onto Rouse Parkway (MD 175) | 5.1 mi | |
| Take the ramp towards I 95 North: Baltimore | 0.4 mi | |
| Merge left onto I 95 N | 4.6 mi | |
| Keep right towards I 895 North | 5.7 mi | |
| Continue onto Harbor Tunnel Throughway (I 895 N) | 1.0 mi | |
| Continue onto Harbor Tunnel Thruway (I 895 N) | 2.2 mi | |
| Continue onto Baltimore Harbor Tunnel (I 895 S) | 1.4 mi | |
| Continue onto Harbor Tunnel Thruway (I 895 S) | 3.7 mi | |
| Keep left onto Express Toll Lanes | 8.0 mi | |
| Merge right onto John F. Kennedy Memorial Highway (I 95 N) | 40.0 mi | |
| Take the ramp towards MD 279: Elkton | 400 feet | |
| Keep left at the fork | 0.3 mi | |
| Keep right towards MD 279 North: Newark Delaware | 0.3 mi | |
| Merge left onto Elkton Road (MD 279) | 3.0 mi | |
| Continue onto South Main Street (DE 896) | 0.7 mi | |
| Go straight onto West Delaware Avenue (DE 273) | 900 feet | |
| You have arrived at your destination | 0 feet |
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Columbia, Maryland - Newark, Delaware