I 75 $south, New York State Thruway
1,166.5 mi19 hours 18 mins
| Head west on Gratiot Avenue (US 41) | 200 feet | |
| Turn left onto US 41 | 34.5 mi | |
| Make a slight left onto US-41 | 9.9 mi | |
| Continue onto North Lincoln Drive (US-41) | 0.4 mi | |
| Turn left onto Scott Street | 0.3 mi | |
| Turn left onto Hancock Street (US-41) | 0.6 mi | |
| Go straight onto Front Street (US-41) | 900 feet | |
| Continue onto Houghton-Hancock Lift Bridge (US 41) | 0.3 mi | |
| Turn left towards US 41 South: Marquette | 300 feet | |
| Turn left onto West Montezuma Avenue (US-41) | 0.7 mi | |
| Go straight onto College Avenue (US 41) | 0.3 mi | |
| Continue onto Townsend Drive (US 41) | 84.8 mi | |
| Enter the roundabout and take the 2nd exit onto Palms Avenue (US 41) | 100 feet | |
| Exit the roundabout onto Palms Avenue (US 41) | 13.3 mi | |
| Enter the roundabout and take the 1st exit onto Marquette Bypass (US 41) | 100 feet | |
| Exit the roundabout onto Marquette Bypass (US 41) | 900 feet | |
| Enter the roundabout and take the 2nd exit onto Marquette Bypass (US 41) | 100 feet | |
| Exit the roundabout onto Marquette Bypass (US 41) | 0.5 mi | |
| Turn right onto South Front Street (US 41) | 50.8 mi | |
| Turn left onto US 2 | 125.3 mi | |
| Take the ramp on the right towards I 75 South: Mackinac Bridge | 0.3 mi | |
| Merge left onto I 75 S | 226.2 mi | |
| Take exit 117B-A towards I 69: Port Huron | 0.2 mi | |
| Keep left towards I 69: Port Huron | 0.4 mi | |
| Keep right towards I 69 East: Port Huron | 1,000 feet | |
| Keep left towards I 69 East: Port Huron | 0.9 mi | |
| Merge left onto I 69 E | 70.1 mi | |
| Continue onto CBSA - Sarnia (Point Edward) Point Of Entry Traveler Lanes (402 E) | 63.9 mi | |
| Merge left onto Highway 401 (401 E) | 31.1 mi | |
| Keep right towards 403: Brantford | 39.9 mi | |
| Take the ramp towards Lincoln M. Alexander Parkway | 0.7 mi | |
| Continue onto Lincoln M. Alexander Parkway | 6.2 mi | |
| Continue onto Red Hill Valley Parkway | 5.3 mi | |
| Keep right towards QEW: Niagara | 1.2 mi | |
| Merge left onto Queen Elizabeth Way (QEW S) | 30.8 mi | |
| Keep left towards 405: Queenston | 5.8 mi | |
| Continue onto Queenston–Lewiston Bridge (405) | 800 feet | |
| Continue onto Lewiston-Queenston Bridge (I 190) | 14.7 mi | |
| Take exit 16 towards I 290 East: Tonawanda | 0.4 mi | |
| Continue onto Youngmann Expressway (I 290 E) | 9.4 mi | |
| Keep left towards I 90 East: Albany | 0.6 mi | |
| Merge left onto New York State Thruway (I 90 E) | 285.1 mi | |
| Take exit 21A towards Massachusetts Turnpike | 0.4 mi | |
| Continue straight | 0.7 mi | |
| Continue onto New York State Thruway Berkshire Connector | 17.3 mi | |
| Merge left onto New York State Thruway Berkshire Connector (I 90 E) | 5.3 mi | |
| Take exit B3 towards NY 22: Austerlitz | 0.4 mi | |
| Turn right onto NY 22 | 8.6 mi | |
| Make a slight left onto State Route 71 (NY 71) | 2.3 mi | |
| Continue onto Green River Valley Road (MA 71) | 1.5 mi | |
| Continue onto Egremont Plain Road (MA 71) | 2.5 mi | |
| Continue onto Creamery Road | 1.7 mi | |
| Go straight onto Main Street (MA 23) | 0.2 mi | |
| Make a sharp left onto Sheffield Road | 1.1 mi | |
| Continue onto Sheffield-Egremont Road | 2.6 mi | |
| Turn right onto North Main Street (US 7) | 0.3 mi | |
| Continue onto Sheffield Plain (US 7) | 2.7 mi | |
| Make a slight left onto US 7 | 2.4 mi | |
| Turn right onto Clayton Road | 0.3 mi | |
| Continue onto School Street | 900 feet | |
| Make a sharp left onto Ashley Falls Road (MA 7A) | 100 feet | |
| You have arrived at your destination |
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Copper Harbor, Michigan - Ashley Falls, Massachusetts