I 40; US 74 $west; US 64 Truck $west, I 40
204.1 mi3 hours 35 mins
| Head northeast on South Main Street (US 29) | 0.2 mi | |
| Make a slight left onto Battleground Road (SC 110) | 2.1 mi | |
| Turn right onto Phillips Drive | 400 feet | |
| Turn right onto Horry Road | 900 feet | |
| Take the ramp on the right | 600 feet | |
| Merge left onto I 85 S | 10.6 mi | |
| Take the ramp towards US 176: Spartanburg | 0.4 mi | |
| Merge left onto North Pine Street (US 176) | 0.4 mi | |
| Go straight onto Asheville Highway (US 176) | 2.7 mi | |
| Turn right onto Frontage Road 5 | 600 feet | |
| Take the ramp | 800 feet | |
| Merge left onto I 26 W | 53.5 mi | |
| Take the ramp on the left towards I 40 West: Canton | 76.4 mi | |
| Take the ramp towards I 81 North: Bristol | 0.4 mi | |
| Merge left onto I 81 N | 7.4 mi | |
| Take exit 8 towards US 25E: Morristown | 0.6 mi | |
| Keep right at the fork | 600 feet | |
| Go straight onto Davy Crockett Parkway (US 25E) | 9.7 mi | |
| Continue onto Dixie Highway (US 25E) | 4.6 mi | |
| Continue onto New Dixie Highway (US 25E) | 1.4 mi | |
| Continue onto New Lee Highway (US 11W) | 0.9 mi | |
| Continue onto Old Lee Highway (US 11W) | 1.4 mi | |
| Continue onto Dixie Highway (US 25E) | 11.6 mi | |
| Continue onto Highway 25E South (US 25E) | 8.8 mi | |
| Turn right to stay on Highway 25E (US 25E) | 900 feet | |
| Turn right onto Cedar Fork Road (SR 345) | 8.5 mi | |
| Turn right onto Alanthus Hill Road (SR 63) | 1.7 mi | |
| You have arrived at your destination, on the left |
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Cowpens, SC, USA - Riley, TN, USA