How to get from Des Moines, Iowa to Henderson, Tennessee

Discover, print or download the driving directions for the best route to go from Des Moines, Iowa to Henderson, Tennessee.

Enlarge the route map Des Moines, Iowa - Henderson, Tennessee

Driving directions from Des Moines, Iowa to Henderson, Tennessee

Avenue of the Saints, I 55 $south

617.6 mi10 hours 3 mins

Head east on East Grand Avenue 1.5 mi
Continue slightly left onto Hubbell Avenue 0.6 mi
Make a slight right onto East University Avenue (IA 163) 7.4 mi
Continue onto Northeast University Avenue (IA 163) 1.8 mi
Continue onto East University Avenue (IA 163) 125.3 mi
Merge left onto Avenue of the Saints (US 34 E) 88.8 mi
Keep left towards US 61 South: Hannibal 6.7 mi
Continue onto McMasters Avenue (US 61 S) 1.1 mi
Continue onto Avenue of the Saints (US 61) 0.7 mi
Continue onto McMasters Avenue (US 61 S) 1.6 mi
Continue onto Avenue of the Saints (US 61 S) 98.7 mi
Take exit 25 towards I 270: Chicago 0.3 mi
Keep right towards I 270 South: Memphis 0.3 mi
Merge left onto I 270 S 11.5 mi
Take exit 1A towards I 55: Saint Louis 0.4 mi
Keep right towards I 55 South: Memphis 0.4 mi
Merge left onto I 55 S 102.7 mi
Keep left onto I 55 S 76.1 mi
Take the ramp on the left towards I 155 East: Caruthersville 0.7 mi
Merge right onto I 155 E 25.7 mi
Take the ramp towards US 51 South: Dyersburg 43.1 mi
Go straight onto Hollywood Drive (US 412 Business) 1.7 mi
Take the ramp on the right 0.2 mi
Merge left onto US 45 Bypass 3.0 mi
Turn right onto South Highland Avenue (US 45) 16.6 mi
Turn left onto West Main Street (TN 365) 0.7 mi
You have arrived at your destination

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Des Moines, Iowa - Henderson, Tennessee

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