How to get from Detroit, Michigan to Cincinnati, Ohio

Discover, print or download the driving directions for the best route to go from Detroit, Michigan to Cincinnati, Ohio.

Enlarge the route map Detroit, Michigan - Cincinnati, Ohio

Driving directions from Detroit, Michigan to Cincinnati, Ohio

I 75 $south, Mill Creek Expressway

259.1 mi4 hours 5 mins

Head west on Michigan Avenue 0.2 mi
Turn right onto Cass Avenue 0.2 mi
Make a slight left onto Grand River Avenue (M 5) 0.3 mi
Turn left onto Vernor Highway West 500 feet
Take the ramp towards I 75 South 0.2 mi
Merge left onto Fisher Freeway (I 75 S) 15.0 mi
Continue onto Detroit-Toledo Expressway (I 75 S) 53.8 mi
Keep left onto I 75 S 138.2 mi
Keep left towards I 75 South: Cincinnati 700 feet
Merge left onto I 75 S 47.6 mi
Take exit 6 towards Mitchell Avenue 900 feet
Keep left at the fork 200 feet
Turn left onto West Mitchell Avenue 0.3 mi
Make a slight right 200 feet
Make a slight right onto Vine Street 2.0 mi
Continue onto Jefferson Avenue 0.5 mi
Make a slight right 300 feet
Go straight onto Calhoun Street 900 feet
Turn left onto Ohio Avenue 300 feet
You have arrived at your destination, on the left

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Detroit, Michigan - Cincinnati, Ohio

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