I 20, GA 49
147.3 mi2 hours 43 mins
| Head northwest on Main Street (SC 23) | 300 feet | |
| Continue onto Jeter Street (SC 23) | 8.1 mi | |
| Keep left onto Martintown Road (SC 230) | 17.0 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto I 20 | 37.0 mi | |
| Take the ramp towards GA 80: Camak | 0.2 mi | |
| Turn left onto Washington Highway (GA 80) | 5.9 mi | |
| Continue onto Railroad Street (GA 80) | 0.3 mi | |
| Make a slight left onto Legion Drive (GA 80) | 0.8 mi | |
| Turn right onto East Main Street (US 278) | 0.7 mi | |
| Make a slight left onto Macon Highway (GA 16) | 22.9 mi | |
| Continue onto Broad Street (GA 15) | 1.1 mi | |
| Continue onto Milledgeville Highway (GA 22) | 11.7 mi | |
| Continue onto Sparta Highway (GA 22) | 12.7 mi | |
| Continue onto GA 49 | 26.8 mi | |
| Turn left onto Gray Highway (US 129) | 0.7 mi | |
| Make a slight left onto 2nd Street (US 129 Alternate) | 0.9 mi | |
| Turn right onto Walnut Street (US 41 Business) | 500 feet | |
| You have arrived at your destination |
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Edgefield, South Carolina - Macon, Georgia