I 75 $south, I 59 $south
369.9 mi5 hours 48 mins
| Head east on Broad Street (US 321) | 100 feet | |
| Make a U-turn and continue on Broad Street (US 321) | 0.6 mi | |
| Continue onto West Elk Avenue (US 321) | 3.6 mi | |
| Continue onto US 321 S | 3.7 mi | |
| Take the ramp | 0.3 mi | |
| Merge right onto I 26 W | 3.1 mi | |
| Continue onto I 26 W | 12.0 mi | |
| Take exit 8A towards I 81 South: Knoxville | 0.2 mi | |
| Merge left onto I 81 S | 57.0 mi | |
| Merge left onto I 40 | 52.7 mi | |
| Keep left towards I 75 South: Chattanooga | 10.2 mi | |
| Keep right onto I 75 S | 800 feet | |
| Keep left onto I 75 S | 72.9 mi | |
| Take the ramp towards I 24 West: Chattanooga | 0.6 mi | |
| Continue towards Chattanooga | 16.7 mi | |
| Take exit 167 on the left towards I 59 South: Birmingham | 0.8 mi | |
| Continue onto I 59 S | 133.9 mi | |
| Take the ramp | 0.8 mi | |
| Turn right onto Reverend Abraham Woods Jr Boulevard | 0.6 mi | |
| Turn left onto 19th Street North | 100 feet | |
| You have arrived at your destination |
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Elizabethton, Tennessee - Birmingham, Alabama