NY 17 $west, New York State Thruway
382.6 mi6 hours 28 mins
| Head southwest on South Main Street (US 209) | 200 feet | |
| Turn right onto Center Street (NY 52) | 11.5 mi | |
| Continue onto State Highway 42 (NY 42) | 0.3 mi | |
| Make a slight right onto Main Street (NY 52) | 1.4 mi | |
| Continue onto State Highway 52 (NY 52) | 1.3 mi | |
| Continue onto Old Monticello Road (NY 52) | 0.4 mi | |
| Continue onto State Highway 52 (NY 52) | 4.5 mi | |
| Turn right onto Triangle Road | 500 feet | |
| Continue straight | 400 feet | |
| Take the ramp | 600 feet | |
| Merge left onto NY 17 W | 81.1 mi | |
| Keep right towards I 81 North: Syracuse | 1.8 mi | |
| Keep left towards I 81 North: Syracuse | 70.1 mi | |
| Take the ramp towards I 690 West: Fairgrounds | 0.2 mi | |
| Merge right towards Fairgrounds | 8.6 mi | |
| Take the ramp towards I 90 | 0.2 mi | |
| Keep left towards I 90 | 0.5 mi | |
| Keep right towards I 90 West: Buffalo | 1,000 feet | |
| Merge left onto New York State Thruway (I 90 W) | 130.0 mi | |
| Take exit 50 towards I 290: Niagara Falls | 0.4 mi | |
| Continue slightly right onto Youngmann Expressway (I 290 W) | 9.5 mi | |
| Keep right towards I 190 North: Niagara Falls | 0.3 mi | |
| Merge left onto Niagara Thruway (I 190 N) | 6.8 mi | |
| Continue onto North Grand Island Bridge (I 190 N) | 0.8 mi | |
| Continue onto Niagara Thruway (I 190 N) | 7.2 mi | |
| Continue onto Queenston–Lewiston Bridge (405) | 800 feet | |
| Continue onto General Brock Parkway (405) | 5.8 mi | |
| Merge left onto Queen Elizabeth Way (QEW N) | 32.3 mi | |
| Take the ramp towards Nikola Tesla Boulevard | 0.7 mi | |
| Continue onto Nikola Tesla Boulevard | 2.0 mi | |
| Go straight onto Burlington Street East | 600 feet | |
| Continue onto Industrial Drive | 0.6 mi | |
| Keep left onto Burlington Street East | 2.0 mi | |
| Turn left onto James Street North | 1.4 mi | |
| Turn right onto Hunter Street West | 800 feet | |
| Turn right | 300 feet | |
| You have arrived at your destination, on the right |
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Ellenville, New York - Hamilton, Ontario