Highway 401, Autoroute des Cantons-de-l'Est
745.8 mi12 hours 46 mins
| Head south on North Van Dyke Road (M 53) | 6.4 mi | |
| Continue onto North Port Crescent Street (M 53) | 0.5 mi | |
| Turn right onto West Huron Avenue (M 53) | 0.5 mi | |
| Continue onto South Van Dyke Road (M 53) | 34.9 mi | |
| Continue onto Main Street (M 53) | 1.5 mi | |
| Continue onto South Van Dyke Road (M 53) | 19.7 mi | |
| Continue onto North Cedar Street (M 53) | 2.2 mi | |
| Continue onto Van Dyke Road (M 53) | 400 feet | |
| Take the ramp on the right towards I 69 East: Port Huron | 0.3 mi | |
| Merge left onto I 69 E | 35.3 mi | |
| Continue onto CBSA - Sarnia (Point Edward) Point Of Entry Traveler Lanes (402 E) | 63.9 mi | |
| Merge left onto Highway 401 (401 E) | 31.1 mi | |
| Keep left onto Highway 401 (401 E) | 66.1 mi | |
| Keep right towards 410 North: Hurontario Street | 4.2 mi | |
| Take the ramp on the left towards 401: Highway 401 East | 0.7 mi | |
| Merge left onto Highway 401 Express (401 E) | 3.8 mi | |
| Keep left towards 401 East | 225.3 mi | |
| Keep left onto Highway 401 (401 E) | 67.7 mi | |
| Continue onto Autoroute du Souvenir (20 E) | 19.6 mi | |
| Continue onto Boulevard Harwood (20) | 1.3 mi | |
| Continue onto Autoroute du Souvenir (20) | 21.0 mi | |
| Take the ramp | 0.2 mi | |
| Keep right at the fork | 0.5 mi | |
| Continue onto 15 sud / 20 est (temp.) (15 S) | 1.3 mi | |
| Continue onto Autoroute 15 (15 S) | 1.2 mi | |
| Continue onto Pont Île-des-Sœurs (15 S) | 0.3 mi | |
| Continue onto Autoroute 15 (15 S) | 0.5 mi | |
| Continue onto Pont Samuel-De Champlain (10) | 2.2 mi | |
| Continue onto 10 est (temp) (10) | 0.3 mi | |
| Continue onto Autoroute des Cantons-de-l'Est (10) | 70.7 mi | |
| Take the ramp towards 55 Sud: Coaticook | 0.6 mi | |
| Merge left onto Autoroute Joseph-Armand Bombardier (55) | 20.9 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto I 91 (I 91 S) | 40.0 mi | |
| Take exit 23 towards US 5: Lyndonville | 0.3 mi | |
| Turn right onto Memorial Drive (US 5) | 0.2 mi | |
| Turn right onto York Street | 300 feet | |
| You have arrived at your destination |
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Filion, Michigan - Lyndon, Town of Lyndon, Vermont