I 40, US 67 $north; Future I 57
375.0 mi6 hours 53 mins
| Head southeast on Garrison Avenue (US 64) | 300 feet | |
| Turn left onto North 11th Street (US 64) | 1.0 mi | |
| Continue onto Midland Boulevard (US 64) | 0.8 mi | |
| Turn right onto Kelley Highway | 1.9 mi | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto I 540 N | 4.5 mi | |
| Keep right towards Little Rock | 119.0 mi | |
| Take the ramp towards US 64 | 0.2 mi | |
| Keep left at the fork | 200 feet | |
| Turn left onto East Oak Street (US 64) | 2.1 mi | |
| Continue onto State Highway 64 (US 64) | 5.2 mi | |
| Continue onto Vilonia Bypass (US 64) | 25.9 mi | |
| Take the ramp on the left onto US 64 | 26.9 mi | |
| Continue onto US 67 N | 67.9 mi | |
| Keep left towards US 67 North: Williams Baptist College | 12.4 mi | |
| Continue onto US 67 | 8.4 mi | |
| Continue onto US 62 | 19.8 mi | |
| Turn left onto North Missouri Avenue (US 67) | 57.4 mi | |
| Take the ramp towards MO 25: Dexter | 0.3 mi | |
| Turn left onto 25 | 20.6 mi | |
| Turn left onto 91 | 0.3 mi | |
| You have arrived at your destination |
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Fort Smith, Arkansas - Advance, Missouri