US 59 $north, I 57 $north
1,007.6 mi16 hours 19 mins
| Head north on 37th Street | 200 feet | |
| Turn left onto Broadway - Avenue J (TX 87) | 1.7 mi | |
| Keep left onto Gulf Freeway (I 45 N) | 40.3 mi | |
| Take the ramp towards I 610 East: Pasadena | 0.5 mi | |
| Merge left onto South Loop East (I 610 N) | 11.3 mi | |
| Take the ramp towards I 69North: Cleveland | 0.2 mi | |
| Merge left onto Eastex Freeway (I 69 N) | 77.5 mi | |
| Continue onto US 59 N | 35.4 mi | |
| Take the ramp towards US 59 North: Nacogdoches | 5.7 mi | |
| Keep right towards US 59 North: Nacogdoches | 15.5 mi | |
| Take the ramp | 0.2 mi | |
| Merge left onto Stallings Drive (Loop 224) | 200 feet | |
| Make a U-turn and continue on Stallings Drive (Loop 224) | 300 feet | |
| Keep left onto Stallings Drive (Loop 224) | 7.8 mi | |
| Take the ramp | 900 feet | |
| Merge left onto North Street (US 59 BUS S) | 200 feet | |
| Make a U-turn and continue on North St (US 59 BUS) | 800 feet | |
| Continue onto US 259 N | 17.0 mi | |
| Turn right onto TX 315 | 24.8 mi | |
| Turn left onto Northwest Loop (TX 149) | 3.3 mi | |
| Take the ramp | 0.3 mi | |
| Turn left onto US 59 BUS | 4.3 mi | |
| Continue onto US 59 N | 21.0 mi | |
| Continue onto E End Blvd South | 900 feet | |
| Merge left onto East End Boulevard South (US 59) | 5.0 mi | |
| Continue onto US 59 N | 37.9 mi | |
| Continue onto US 59 | 2.9 mi | |
| Turn left onto US 59 N | 9.5 mi | |
| Continue onto US 59 S | 12.0 mi | |
| Turn left onto Chelf Road | 900 feet | |
| Take the ramp | 0.3 mi | |
| Merge left onto Jarvis Parkway (I 369 N) | 3.3 mi | |
| Keep right towards I 30 East: Little Rock | 24.1 mi | |
| Continue onto I 30 | 116.9 mi | |
| Keep left onto I 30 | 0.7 mi | |
| Continue onto I 30 | 4.2 mi | |
| Keep right towards I 40 East: Jacksonville | 1.6 mi | |
| Keep right onto I 40 | 121.8 mi | |
| Take the ramp towards I 55 North: Blytheville | 0.7 mi | |
| Merge right onto I 55 N | 130.7 mi | |
| Take the ramp towards I 57 North: Chicago | 0.5 mi | |
| Merge left onto Interstate 57 (I 57 N) | 115.8 mi | |
| Continue onto I 57 N | 69.4 mi | |
| Keep left towards I 57 North: Chicago | 74.0 mi | |
| Take exit 237B towards I 74 West: Peoria | 0.3 mi | |
| Merge left onto I 74 W | 6.9 mi | |
| Take the ramp towards IL 47: Gibson City | 0.3 mi | |
| Turn left onto County Road 400 E (IL 47) | 500 feet | |
| Continue onto N Lombard St (IL 47) | 0.5 mi | |
| Turn right onto East Oak Street (US 150) | 0.3 mi | |
| You have arrived at your destination |
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Galveston, Texas - Mahomet, Illinois