I 81 $north, I 81 $north; US 58
162.2 mi2 hours 35 mins
| Head southeast on Woodland Street | 0 feet | |
| Turn right onto East Jackson Street (SR 71) | 300 feet | |
| Make a sharp left onto Kane Street (US 23 Business) | 0.7 mi | |
| Turn left onto US 23 | 1.0 mi | |
| Turn left onto US 58 | 0.3 mi | |
| Continue onto SR 224 | 4.6 mi | |
| Turn left onto Bloomingdale Pike | 5.1 mi | |
| Turn right onto Ollis Bowers Hill Road | 400 feet | |
| Turn left onto East Stone Drive (US 11W) | 9.7 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto I 81 N | 137.6 mi | |
| Take the ramp towards VA 112: Salem | 0.3 mi | |
| Turn right onto Wildwood Road (VA 112) | 0.4 mi | |
| Turn left onto West Main Street (US 11) | 2.1 mi | |
| You have arrived at your destination |
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Gate City, Virginia - Salem, Virginia