James Madison Highway, James Monroe Highway
145.9 mi2 hours 54 mins
| Head north on North Main Street (US 15 N) | 200 feet | |
| Exit the roundabout onto US 15 N | 8.5 mi | |
| Turn right onto South Madison Road (US 15 N) | 1.4 mi | |
| Continue onto James Madison Highway (US 15 N) | 5.8 mi | |
| Continue straight to stay on James Madison Highway (US 15 N) | 10.0 mi | |
| Take the ramp on the right towards US 15 North | 0.3 mi | |
| Merge left onto James Madison Highway (US 15 N) | 23.5 mi | |
| Continue onto Eastern Bypass (US 15 N) | 2.3 mi | |
| Keep left towards US 15 North | 0.8 mi | |
| Continue onto Lee Highway (US 15) | 7.3 mi | |
| Turn left onto James Madison Highway (US 15 N) | 11.1 mi | |
| Continue onto James Monroe Highway (US 15 N) | 2.3 mi | |
| Enter the roundabout and take the 2nd exit onto James Monroe Highway (US 15 N) | 100 feet | |
| Exit the roundabout onto James Monroe Highway (US 15 N) | 0.3 mi | |
| Enter the roundabout and take the 2nd exit onto James Monroe Highway (US 15 N) | 200 feet | |
| Exit the roundabout onto James Monroe Highway (US 15 N) | 9.1 mi | |
| Continue onto South King Street (US 15 N) | 1.3 mi | |
| Take the ramp on the right towards US 15 North: Alexandria | 0.2 mi | |
| Merge left onto Leesburg Bypass (US 15 N) | 4.1 mi | |
| Continue onto James Monroe Highway (US 15 N) | 10.0 mi | |
| Continue onto Catoctin Mountain Highway (US 15) | 1.4 mi | |
| Enter the roundabout and take the 2nd exit onto Catoctin Mountain Highway (US 15) | 200 feet | |
| Exit the roundabout onto Catoctin Mountain Highway (US 15) | 5.8 mi | |
| Merge left onto Jefferson National Pike (US 15 N) | 4.6 mi | |
| Continue onto South Jefferson Street | 700 feet | |
| Take the ramp on the left towards US 15 North | 900 feet | |
| Merge left onto Frederick Freeway (US 15 N) | 3.1 mi | |
| Continue onto Catoctin Mountain Highway (US 15 N) | 28.4 mi | |
| Take the ramp towards PA 134 | 1,000 feet | |
| Turn left onto Taneytown Road (PA 134) | 3.1 mi | |
| Continue onto South Washington Street (PA 134) | 500 feet | |
| Make a slight right onto Steinwehr Avenue (US 15 Business N) | 0.2 mi | |
| Turn left onto Baltimore Street (US 15 Business N) | 0.4 mi | |
| You have arrived at your destination |
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Gordonsville, Virginia - Gettysburg, Pennsylvania