How to get from Greenville, SC to SD

Discover, print or download the driving directions for the best route to go from Greenville, SC to SD.

Enlarge the route map Greenville, SC - SD

Driving directions from Greenville, SC to SD

I 40, I 29 $north

1,477.7 mi22 hours 2 mins

Head northeast on South Main Street 0.4 mi
Turn left onto College Street 0.3 mi
Continue slightly right onto Buncombe Street (SC 183) 0.3 mi
Turn right onto Rutherford Street 0.6 mi
Continue onto Poinsett Highway (US 276) 6.0 mi
Take the ramp 0.3 mi
Merge left onto US 25 26.6 mi
Keep left towards I 26 West: Hendersonville 10.5 mi
Continue onto I 26 W 12.5 mi
Take the ramp on the left towards I 40 West: Canton 129.7 mi
Keep right towards Nashville 154.6 mi
Keep right towards I 24 West: Nashville 2.1 mi
Keep right towards I 24 West: Clarksville 4.8 mi
Keep left towards I 24 West: Clarksville 112.6 mi
Keep right onto I 24 W 63.5 mi
Keep left towards I 57 North: Chicago 0.4 mi
Merge left towards Mount Vernon 51.7 mi
Take the ramp on the left towards I 64 West: Saint Louis 70.7 mi
Take the ramp towards I 70 West: Kansas City 0.7 mi
Merge right onto I 70 W 248.8 mi
Keep right towards I 70 West: Saint Joseph 0.8 mi
Keep right towards I 29 North: Saint Joseph 4.6 mi
Keep left towards I 29 North: K.C.I. Airport 14.2 mi
Merge left onto I 29 N 2.7 mi
Keep left towards I 29 North: Saint Joseph 37.2 mi
Continue onto I 29 N 119.5 mi
Take the ramp towards Downtown 0.3 mi
Turn left onto South Expressway 1.5 mi
Continue onto South 6th Street 0.4 mi
Turn left onto West Broadway 200 feet
Keep right onto West Broadway 300 feet
Turn left onto West Broadway 0.7 mi
Turn right onto North 16th Street 1.4 mi
Take the ramp 0.5 mi
Merge left onto I 29 N 179.0 mi
Take the ramp towards I 90 West: Rapid City 0.3 mi
Merge left onto Purple Heart Memorial Highway (I 90) 182.8 mi
Take the ramp towards US 83 North: Pierre State Capitol 0.4 mi
Keep left at the fork 300 feet
Turn right onto US 83 33.8 mi
Turn left onto South Pierre Street (US 14) 800 feet
Continue left onto South Euclid Avenue (US 14) 700 feet
You have arrived at your destination

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Greenville, SC - SD

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