I 74 $west, I 74 $west; US 421 $north
636.9 mi10 hours 24 mins
| Head north on South High Street (US 62) | 0 feet | |
| Turn left onto West Main Street (US 50) | 700 feet | |
| Turn right onto North West Street (SR 73) | 9.4 mi | |
| Continue onto South South Street (SR 73) | 20.5 mi | |
| Take the ramp on the left towards I 71 South: Cincinnati | 0.3 mi | |
| Merge left onto I 71 S | 8.4 mi | |
| Continue onto I 71 W | 3.5 mi | |
| Continue onto I 71 S | 14.8 mi | |
| Take exit 17B towards I 275 West | 0.9 mi | |
| Merge left onto Cincinnati By-Pass (I 275 W) | 22.8 mi | |
| Keep left towards I 74 West: Indianapolis | 83.9 mi | |
| Continue towards Southeastern Avenue | 1.2 mi | |
| Continue onto Southeastern Avenue | 0.8 mi | |
| Make a slight left onto East Raymond Street | 3.4 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto I 65 N | 0.7 mi | |
| Take exit 110B on the left towards I 70 West: Saint Louis | 0.6 mi | |
| Merge left onto I 70 | 3.7 mi | |
| Take the ramp towards Holt Road | 0.3 mi | |
| Turn right onto South Holt Road | 0.7 mi | |
| Turn left onto Rockville Road | 2.1 mi | |
| Take the ramp on the right | 0.5 mi | |
| Merge left onto I 74 W | 1.8 mi | |
| Continue onto I 74 | 0.2 mi | |
| Continue onto I 74:I 465 W | 400 feet | |
| Keep right onto I 74 W | 165.8 mi | |
| Take the ramp towards I-74 West: Peoria | 28.4 mi | |
| Keep right towards I 74 West: Peoria | 91.9 mi | |
| Keep left onto I 80 | 50.6 mi | |
| Take the ramp towards West Liberty | 0.3 mi | |
| Turn right onto Garfield Avenue | 4.5 mi | |
| Turn right onto Cedar Valley Road | 1.0 mi | |
| Turn left onto Harding Avenue | 1.7 mi | |
| Go straight onto Green Road | 1.1 mi | |
| Continue onto Garfield Avenue | 6.5 mi | |
| Continue onto 160th Street | 0.5 mi | |
| Continue onto Fox Avenue (CR X40) | 3.0 mi | |
| Turn left onto US 30 | 14.6 mi | |
| Take the ramp | 0.4 mi | |
| Continue onto US 151 N | 24.6 mi | |
| Turn left onto Linn Street | 0.6 mi | |
| Continue slightly left onto Railroad Street | 400 feet | |
| Turn right to stay on Railroad Street | 500 feet | |
| Continue onto Coggon Road (CR D62) | 2.4 mi | |
| Turn right onto Robinson Road | 1.0 mi | |
| Continue onto 110th Avenue | 11.9 mi | |
| Turn left onto 220th Street (CR D22) | 3.5 mi | |
| Turn right onto Washburn Avenue (IA 187) | 12.1 mi | |
| Continue onto C Avenue (IA 187) | 3.0 mi | |
| Enter the roundabout and take the 2nd exit onto C Avenue (IA 187) | 200 feet | |
| Exit the roundabout onto C Avenue (IA 187) | 3.1 mi | |
| Go straight onto Eisenhower Road (IA 187) | 1.0 mi | |
| Continue onto Main Street (IA 187) | 1.0 mi | |
| Go straight onto Eisenhower Road (IA 187) | 1.6 mi | |
| Continue onto 90th Street (IA 187) | 5.1 mi | |
| Turn right onto K Avenue (IA 187) | 5.0 mi | |
| Continue onto State Highway 150 (IA 150) | 1.1 mi | |
| Continue onto Lincoln Road (IA 150) | 7.1 mi | |
| Continue onto State Highway 150 (IA 150) | 1.1 mi | |
| Turn right onto West Bradford Street (US 18) | 0.3 mi | |
| You have arrived at your destination |
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Hillsboro, Ohio - West Union, Iowa