I 40, Dwight D. Eisenhower Highway
1,015.2 mi14 hours 35 mins
| Head southeast on Cedarglade Road | 400 feet | |
| Turn right to stay on Cedarglade Road | 0.6 mi | |
| Make a slight left onto Cedar Street | 0.4 mi | |
| Turn left onto Whittington Avenue | 200 feet | |
| Turn right onto Central Avenue (AR 7) | 0.6 mi | |
| Turn left onto Spring Street | 0.9 mi | |
| Turn left onto East Grand Avenue (US 70B) | 22.7 mi | |
| Take the ramp onto US 70 E | 0.2 mi | |
| Keep left onto US 70 E | 18.2 mi | |
| Take the ramp towards I 430 North: Fort Smith | 0.7 mi | |
| Continue onto I 430 N | 12.4 mi | |
| Keep left towards I 40 West: Fort Smith | 0.8 mi | |
| Merge left onto I 40 | 191.3 mi | |
| Take exit 286 towards OK 351: Muskogee | 0.4 mi | |
| Continue onto Muskogee Turnpike (OK 351 W) | 14.4 mi | |
| Keep right onto Muskogee Turnpike (OK 351) | 41.3 mi | |
| Continue onto Disabled American Veterans Highway (OK 51) | 3.4 mi | |
| Continue onto Broken Arrow Expressway (OK 51) | 2.6 mi | |
| Take the ramp towards US 169 North: Owasso | 0.3 mi | |
| Merge left onto Representative Sue Tibbs Memorial Highway (US 169 N) | 2.9 mi | |
| Continue onto Pearl Harbor Memorial Expressway (US 169 N) | 1.3 mi | |
| Take the ramp towards I 244: Joplin | 600 feet | |
| Keep left towards I 244 West: Oklahoma City | 0.5 mi | |
| Merge left onto Martin Luther King, Junior Memorial Expressway (I 244 W) | 7.6 mi | |
| Take exit 5B on the left towards US 64 West: Sand Springs | 24.4 mi | |
| Continue onto Cimarron Turnpike (US 412 W) | 44.4 mi | |
| Keep right towards US 177: Noble | 14.4 mi | |
| Take the ramp towards I 35 North | 0.4 mi | |
| Merge left onto World War II Veterans Memorial Highway (I 35 N) | 41.4 mi | |
| Continue onto Kansas Turnpike (I 35 N) | 41.7 mi | |
| Take the ramp towards I 135: South Wichita | 0.6 mi | |
| Continue onto I 135 N | 95.7 mi | |
| Take the ramp towards I-70 West | 0.2 mi | |
| Merge left onto Dwight D. Eisenhower Highway (I 70) | 243.1 mi | |
| Continue onto I 70 | 7.2 mi | |
| Continue onto I 70 W | 169.4 mi | |
| Keep left onto I 70 W | 4.4 mi | |
| Take exit 275B towards CO 265 | 0.2 mi | |
| Make a sharp left onto Brighton Boulevard (CO 265) | 700 feet | |
| Keep left onto Brighton Boulevard | 1.5 mi | |
| Continue onto Broadway | 1.8 mi | |
| Turn left onto East 14th Avenue | 700 feet | |
| You have arrived at your destination |
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Hot Springs National Park, Arkansas - Denver, Colorado