US 23 $south, I 75 $south
1,520.4 mi23 hours 27 mins
| Head north on 11 1/4 Road | 1.1 mi | |
| Turn right onto West 48 Road | 0.7 mi | |
| Turn left onto South 13 Road | 2.0 mi | |
| Turn right onto Caberfae Highway (M 55) | 12.6 mi | |
| Turn right onto Cadillac Highway (M 115) | 18.1 mi | |
| Continue onto State Highway 115 (M 115) | 19.6 mi | |
| Take the ramp on the right towards US 10 East | 0.3 mi | |
| Merge left onto US 10 E | 6.6 mi | |
| Keep left towards US 10 East: Bay City | 4.3 mi | |
| Take the ramp on the left towards US 10 East: Midland | 45.8 mi | |
| Take exit 140A towards I 75 South: Saginaw | 0.6 mi | |
| Merge left onto I 75 S | 47.2 mi | |
| Take the ramp towards US 23: Ann Arbor | 600 feet | |
| Continue towards US 23: Ann Arbor | 45.3 mi | |
| Keep left towards US 23 South: Plymouth | 0.5 mi | |
| Continue onto US 23 S | 1.9 mi | |
| Keep right towards US 23 South: Ann Arbor | 0.6 mi | |
| Continue onto US 23 S | 57.9 mi | |
| Continue onto I 475 S | 700 feet | |
| Take exit 1A towards I 75 South: Dayton | 0.6 mi | |
| Merge right onto I 75 S | 137.2 mi | |
| Keep left towards I 75 South: Cincinnati | 700 feet | |
| Merge left onto I 75 S | 299.9 mi | |
| Take the ramp towards I 75 South: Nashville | 3.5 mi | |
| Keep right towards I 75 South: Nashville | 17.1 mi | |
| Keep left towards I 75 South: Chattanooga | 10.2 mi | |
| Keep right onto I 75 S | 800 feet | |
| Keep left onto I 75 S | 49.5 mi | |
| Take the ramp towards SR 60: Cleveland | 1,000 feet | |
| Turn right onto Georgetown Road Northwest (TN 60) | 1,000 feet | |
| Continue onto 25th Street Northwest (TN 60) | 4.1 mi | |
| Continue onto Appalachian Highway (US 74) | 1.7 mi | |
| Turn left onto McGrady Drive Southeast (TN 60) | 0.2 mi | |
| Turn left onto Dalton Pike (TN 60) | 10.7 mi | |
| Continue onto Cleveland Road (GA 71) | 9.1 mi | |
| Continue onto Cleveland Highway (GA 71) | 4.5 mi | |
| Turn right onto North Bypass (US 41) | 2.1 mi | |
| Continue onto Chattanooga Road (US 41) | 0.6 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 75 S | 90.3 mi | |
| Continue onto James Wendell George Parkway (I 75 S) | 2.3 mi | |
| Keep left onto I 75 S | 64.9 mi | |
| Take the ramp towards I 475 South: Valdosta | 15.6 mi | |
| Keep left towards I 75 South: Valdosta | 0.6 mi | |
| Merge left onto I 75 S | 300.1 mi | |
| Keep right towards I 75 South: Tampa | 53.5 mi | |
| Keep left towards South I 75: Naples | 16.2 mi | |
| Continue onto I 75 S | 58.3 mi | |
| Keep left onto I 75 S | 62.3 mi | |
| Take the ramp towards SR 82: Dr. Martin Luther King Jr. Blvd. | 0.4 mi | |
| Turn left onto Dr Martin Luther King Boulevard (FL 82) | 800 feet | |
| Continue onto SR 82 (FL 82) | 25.4 mi | |
| Make a slight right to stay on Immokalee Road (FL 82) | 200 feet | |
| Go straight onto FL 29 | 5.5 mi | |
| Turn right onto Immokalee Road (CR 846) | 3.0 mi | |
| Turn left onto Camp Keais Road | 2.6 mi | |
| Turn right onto Pope John Paul II Boulevard | 1.0 mi | |
| Enter the roundabout and take the 2nd exit onto Pope John Paul II Boulevard | 100 feet | |
| Exit the roundabout onto Pope John Paul II Boulevard | 0.2 mi | |
| Turn right onto Annunciation Circle | 700 feet | |
| Turn left onto Ave Maria Boulevard | 100 feet | |
| You have arrived at your destination |
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Hoxeyville, South Branch Twp, Michigan - Ave Maria, Florida