I 24 $west, I 44 $west
630.6 mi9 hours 50 mins
| Head northwest on Madison Street | 100 feet | |
| Turn right onto South Side Square | 400 feet | |
| Turn left onto East Side Square | 400 feet | |
| Continue onto Washington Street Southeast | 400 feet | |
| Continue onto Washington Street Northeast | 0.6 mi | |
| Turn left onto Pratt Avenue Northeast | 0.3 mi | |
| Continue onto University Drive Northwest | 1.9 mi | |
| Make a slight right | 200 feet | |
| Turn right onto Jordan Lane Northwest (SR 53) | 2.3 mi | |
| Continue onto Ardmore Hwy (SR 53) | 5.9 mi | |
| Continue onto Ardmore Highway (SR 53) | 16.2 mi | |
| Continue onto SR 7 | 0.4 mi | |
| Take the ramp on the right towards Nashville | 0.2 mi | |
| Merge left onto I 65 N | 51.6 mi | |
| Keep left onto I 65 N | 29.3 mi | |
| Keep right towards Knoxville | 0.3 mi | |
| Merge left onto I 40 | 700 feet | |
| Continue towards I 24 West: Clarksville | 0.5 mi | |
| Keep left towards I 24 West: Clarksville | 0.4 mi | |
| Merge right onto I 24 W | 2.3 mi | |
| Keep right towards I 24 West: Clarksville | 2.1 mi | |
| Keep left towards I 24 West: Clarksville | 112.6 mi | |
| Keep right onto I 24 W | 63.5 mi | |
| Keep left towards I 57 North: Chicago | 0.4 mi | |
| Merge left towards Mount Vernon | 51.7 mi | |
| Take the ramp on the left towards I 64 West: Saint Louis | 72.4 mi | |
| Keep right towards IL 3 South: Cahokia | 1.6 mi | |
| Keep right towards I 44: Tulsa | 1.4 mi | |
| Keep right onto I 44 W | 160.9 mi | |
| Take exit 129 towards MO 32: Hartville | 900 feet | |
| Turn right onto South Jefferson Avenue (MO 5) | 2.2 mi | |
| Continue onto North Jefferson Street (MO 64) | 28.7 mi | |
| Turn right onto US 65 N | 13.7 mi | |
| Turn left onto US 54 | 6.4 mi | |
| Turn left onto Jackson Street (254) | 400 feet | |
| You have arrived at your destination |
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Huntsville, Alabama - Hermitage, Missouri