IL 4, I 64 $east
239.9 mi3 hours 52 mins
| Head east on West Walnut Street (IL 78) | 600 feet | |
| Turn right onto North Main Street | 0.7 mi | |
| Turn right onto North Central Park Plaza | 200 feet | |
| Turn left onto North Sandy Street | 400 feet | |
| Turn left onto South Central Park Plaza | 200 feet | |
| Turn right onto South Main Street | 0.7 mi | |
| Turn left onto East Morton Avenue (I 72 Bus) | 2.5 mi | |
| Continue onto Old Route 36 (I 72 Business) | 0.9 mi | |
| Turn left onto I 72 Business E | 0.3 mi | |
| Merge left onto I 72 E | 27.7 mi | |
| Continue onto I 72 | 0.2 mi | |
| Take exit 97A towards I 55 South: Saint Louis | 0.7 mi | |
| Merge right onto Interstate 55 (I 55 S) | 58.2 mi | |
| Take the ramp towards IL 4: Staunton | 0.3 mi | |
| Turn left onto IL 4 | 26.7 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 64 E | 50.1 mi | |
| Keep right towards I 57 South | 4.6 mi | |
| Take the ramp on the left towards I 64 East: Louisville | 64.2 mi | |
| Take exit 12 towards SR 165: Poseyville | 0.4 mi | |
| Turn right onto SR 165 | 0.9 mi | |
| Turn right onto East Main Street (SR 68) | 0.2 mi | |
| You have arrived at your destination |
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Jacksonville, Illinois - Poseyville, Indiana