How to get from Kansas City, KS, USA to Sikeston, MO, USA

Discover, print or download the driving directions for the best route to go from Kansas City, KS, USA to Sikeston, MO, USA.

Enlarge the route map Kansas City, KS, USA - Sikeston, MO, USA

Driving directions from Kansas City, KS, USA to Sikeston, MO, USA

I 70 $east; US 40 $east, I 55 $south

382.3 mi5 hours 46 mins

Head east on Ann Avenue 900 feet
Turn left onto North 7th Street Trafficway (US 69 N) 700 feet
Turn right onto Minnesota Avenue 0.4 mi
Take the ramp towards I 70 East: Saint Louis 0.2 mi
Merge right onto Lewis and Clark Viaduct (I 70 E) 1.1 mi
Take exit 2A towards I 35 South: Wichita 0.3 mi
Merge left onto I 35 S 0.5 mi
Take the ramp on the left towards Saint Louis 0.5 mi
Merge left onto I 670 E 0.5 mi
Keep left towards I 70 East: Saint Louis 0.4 mi
Merge left onto Truman/Eisenhower Presidential Highway (I 70 E) 29.1 mi
Continue onto I 70 E 69.3 mi
Keep left onto I 70 E 108.5 mi
Take exit 210A towards I 64 East: Chesterfield 25.3 mi
Take exit 25 towards I 270: Chicago 0.3 mi
Keep right towards I 270 South: Memphis 0.3 mi
Merge left onto I 270 S 11.5 mi
Take exit 1A towards I 55: Saint Louis 0.4 mi
Keep right towards I 55 South: Memphis 0.4 mi
Merge left onto I 55 S 102.7 mi
Keep left onto I 55 S 26.5 mi
Take the ramp towards US 62: Sikeston 900 feet
Keep left at the fork 100 feet
Turn left onto East Malone Avenue (US 62) 3.2 mi
Turn right onto North New Madrid Street 600 feet
Turn left onto West Center Street 300 feet
You have arrived at your destination, on the left

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Kansas City, KS, USA - Sikeston, MO, USA

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