I 65 $north, I 85 $north
731.1 mi11 hours 27 mins
| Head northeast on Johnston Street (US 167) | 0.4 mi | |
| Continue onto Louisiana Avenue (US 167) | 3.5 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto I 10 | 54.3 mi | |
| Take the ramp on the left | 0.8 mi | |
| Continue onto I 12 | 84.4 mi | |
| Keep left at the fork | 0.4 mi | |
| Keep left towards I 10: Bay Saint Louis | 0.7 mi | |
| Merge left onto I 10 | 102.5 mi | |
| Take the ramp on the left towards I 65 North: Montgomery | 0.6 mi | |
| Continue onto I 65 N | 170.5 mi | |
| Take exit 171 towards 85: Atlanta | 0.3 mi | |
| Continue onto I 85 N | 161.8 mi | |
| Continue onto James Wendell George Parkway (I 75 N) | 2.6 mi | |
| Keep left towards I 85 North: Greenville | 21.3 mi | |
| Take the ramp towards GA 316 East: Lawrenceville | 0.5 mi | |
| Continue onto University Parkway (GA 316 E) | 7.4 mi | |
| Keep left onto University Parkway (GA 316 E) | 31.6 mi | |
| Take the ramp onto US 29 | 0.5 mi | |
| Merge left onto Athens Perimeter (US 29) | 9.0 mi | |
| Continue onto US 29 | 1.2 mi | |
| Keep right onto Hull Road (GA 72) | 2.6 mi | |
| Continue onto Hull Colbert Road (GA 72) | 4.6 mi | |
| Continue onto 3rd Avenue (GA 72) | 1.2 mi | |
| Continue onto Colbert-Comer Road (GA 72) | 20.8 mi | |
| Continue onto College Avenue (SR 17) | 1.2 mi | |
| Continue onto Elbert Street (GA 17) | 0.7 mi | |
| Continue onto Heard Street (GA 17) | 500 feet | |
| Continue onto Elbert Street (GA 17) | 1.2 mi | |
| Turn left onto Calhoun Falls Highway (GA 72) | 13.1 mi | |
| Continue onto SC 72 | 27.7 mi | |
| Turn right onto State Highway 72 (SC 72 Business) | 1.3 mi | |
| Continue onto West Cambridge Avenue (SC 72 Business) | 1.4 mi | |
| Turn right onto Hampton Avenue (US 25 Business) | 0.2 mi | |
| Continue slightly right onto Ivy Hall Lane (US 25 Business) | 400 feet | |
| Continue onto Main Street North (US 25 Business) | 600 feet | |
| Turn right onto Maxwell Avenue (SC 10) | 100 feet | |
| You have arrived at your destination |
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Lafayette, Louisiana - Greenwood, South Carolina