I 10, US 285
750.6 mi12 hours 27 mins
| Head west on Lafayette Street (US 59 Business) | 100 feet | |
| Turn right onto San Dario Avenue | 400 feet | |
| Take the ramp on the left | 800 feet | |
| Merge left onto I 35 N | 138.1 mi | |
| Take the ramp towards Loop 1604: Somerset | 0.3 mi | |
| Make a slight left onto Interstate Highway 35 Frontage Road | 600 feet | |
| Turn left onto Anderson Loop (Loop 1604) | 8.1 mi | |
| Keep left onto Anderson Loop (Loop 1604 N) | 16.9 mi | |
| Take the ramp towards I 10: San Antonio | 0.3 mi | |
| Keep left towards I 10 West: El Paso | 0.2 mi | |
| Keep right towards I 10 West: El Paso | 0.3 mi | |
| Keep left towards I 10 West | 0.3 mi | |
| Merge left onto Interstate 10 West (I 10) | 298.6 mi | |
| Take the ramp towards US 285 | 0.2 mi | |
| Continue onto Northwest 10 Frontage Road | 900 feet | |
| Turn right onto US 285 | 134.7 mi | |
| Keep right onto South Canal Street (US 285) | 3.4 mi | |
| Continue onto West Pierce Street (US 285) | 3.4 mi | |
| Continue onto Artesia Highway (US 285) | 2.1 mi | |
| Continue onto Seven Rivers Highway (US 285) | 25.4 mi | |
| Continue onto South 1st Street (US 285) | 0.6 mi | |
| Continue onto Seven Rivers Highway (US 285) | 0.2 mi | |
| Continue onto South 1st Street (US 285) | 5.2 mi | |
| Continue onto Roswell Highway (US 285) | 7.2 mi | |
| Continue onto Southeast Main Street (US 285) | 26.5 mi | |
| Turn left onto Relief Route (US 285 Truck) | 7.9 mi | |
| Turn left onto West 2nd Street (US 70) | 67.1 mi | |
| Go straight onto Sudderth Drive (NM 48) | 3.3 mi | |
| You have arrived at your destination |
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Laredo, Texas - Ruidoso, New Mexico