I 70 $east, I 70 $east; US 40 $east
347.6 mi5 hours 25 mins
| Head east on West 6th Street | 400 feet | |
| Continue onto New Hampshire Street | 0.6 mi | |
| Turn left onto East 11th Street | 0.6 mi | |
| Continue right onto Haskell Avenue | 1.5 mi | |
| Turn left onto East 23rd Street | 1.9 mi | |
| Take the ramp onto East 23rd Street | 0.8 mi | |
| Keep left at the fork | 0.7 mi | |
| Merge left onto KS 10 | 22.4 mi | |
| Keep left towards I 435 East | 0.2 mi | |
| Merge left onto I 435 | 12.2 mi | |
| Keep left towards I 435 North: Des Moines | 9.1 mi | |
| Take exit 63B towards I 70 East: Saint Louis | 0.8 mi | |
| Keep left towards I 70 East: Saint Louis | 500 feet | |
| Merge left onto Truman/Eisenhower Presidential Highway (I 70 E) | 92.2 mi | |
| Keep left onto I 70 E | 108.5 mi | |
| Take exit 210A towards I 64 East: Chesterfield | 25.3 mi | |
| Take exit 25 towards I 270: Chicago | 0.3 mi | |
| Keep right towards I 270 South: Memphis | 0.3 mi | |
| Merge left onto I 270 S | 11.5 mi | |
| Take exit 1A towards I 55: Saint Louis | 0.4 mi | |
| Keep right towards I 55 South: Memphis | 0.4 mi | |
| Merge left onto I 55 S | 21.7 mi | |
| Take the ramp towards US 67 South: Farmington | 0.5 mi | |
| Merge left onto US 67 | 33.5 mi | |
| Keep left towards MO 32 East: Farmington | 1.6 mi | |
| Turn right onto North Washington Street (MO D) | 0.5 mi | |
| Turn left onto East Columbia Street | 100 feet | |
| You have arrived at your destination |
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Lawrence, Kansas - Farmington, Missouri