I 75 $south, Florida's Turnpike
866.3 mi13 hours 10 mins
| Head northeast on South Broadway (US 27) | 500 feet | |
| Turn right onto West Short Street | 0.8 mi | |
| Turn left onto Midland Avenue (US 60) | 0.4 mi | |
| Continue right onto Winchester Road (US 60) | 3.3 mi | |
| Take the ramp | 0.2 mi | |
| Merge left onto I 75 S | 163.1 mi | |
| Take the ramp towards I 75 South: Nashville | 3.5 mi | |
| Keep right towards I 75 South: Nashville | 17.1 mi | |
| Keep left towards I 75 South: Chattanooga | 10.2 mi | |
| Keep right onto I 75 S | 800 feet | |
| Keep left onto I 75 S | 49.5 mi | |
| Take the ramp towards SR 60: Cleveland | 1,000 feet | |
| Turn right onto Georgetown Road Northwest (TN 60) | 1,000 feet | |
| Continue onto 25th Street Northwest (TN 60) | 4.1 mi | |
| Continue onto Appalachian Highway (US 74) | 1.7 mi | |
| Turn left onto McGrady Drive Southeast (TN 60) | 0.2 mi | |
| Turn left onto Dalton Pike (TN 60) | 10.7 mi | |
| Continue onto Cleveland Road (GA 71) | 9.1 mi | |
| Continue onto Cleveland Highway (GA 71) | 4.5 mi | |
| Turn right onto North Bypass (US 41) | 2.1 mi | |
| Continue onto Chattanooga Road (US 41) | 0.6 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 75 S | 90.3 mi | |
| Continue onto James Wendell George Parkway (I 75 S) | 2.3 mi | |
| Keep left onto I 75 S | 64.9 mi | |
| Take the ramp towards I 475 South: Valdosta | 15.6 mi | |
| Keep left towards I 75 South: Valdosta | 0.6 mi | |
| Merge left onto I 75 S | 300.1 mi | |
| Keep left towards South Turnpike | 42.1 mi | |
| Keep left onto Florida's Turnpike | 11.6 mi | |
| Take the ramp towards FL 528 Toll: International Airport | 0.4 mi | |
| Keep left at the fork | 1.2 mi | |
| Merge left onto Beachline Expressway (FL 528 Toll E) | 40.6 mi | |
| Continue onto Bennett Causeway (FL 528 E) | 8.5 mi | |
| Continue onto Astronaut Boulevard (FL A1A) | 1.2 mi | |
| Continue onto North Atlantic Avenue (FL A1A) | 4.2 mi | |
| Continue onto North Orlando Avenue (FL A1A) | 0.6 mi | |
| You have arrived at your destination |
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Lexington, Kentucky - Cocoa Beach, Florida