How to get from Lexington-Fayette, KY, USA to St. Louis, MO, USA

Discover, print or download the driving directions for the best route to go from Lexington-Fayette, KY, USA to St. Louis, MO, USA.

Enlarge the route map Lexington-Fayette, KY, USA - St. Louis, MO, USA

Driving directions from Lexington-Fayette, KY, USA to St. Louis, MO, USA

I 64 $west, I 64 $west; US 50 $west

338.9 mi5 hours 7 mins

Head southwest on Bryan Avenue 100 feet
Turn right onto Arceme Avenue 0.3 mi
Turn right onto North Limestone 0.6 mi
Turn left onto New Circle Road (KY 4) 0.2 mi
Turn right onto North Broadway (US 27) 1.2 mi
Turn left 0.5 mi
Merge left onto I 64 W 4.1 mi
Keep left towards I 64 West: Frankfort 250.3 mi
Keep right towards I 57 North 4.6 mi
Take the ramp on the left towards I 64 West: Saint Louis 72.4 mi
Keep right towards IL 3 South: Cahokia 1.6 mi
Keep left towards I 64 West 2.2 mi
Take exit 38A towards Forest Park Avenue 0.4 mi
Go straight onto Forest Park Avenue 0.4 mi
Turn right onto South Spring Avenue 500 feet
Turn left onto Laclede Avenue 800 feet
You have arrived at your destination, on the right

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Lexington-Fayette, KY, USA - St. Louis, MO, USA

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