How to get from Lexington, Kentucky to Columbia, South Carolina

Discover, print or download the driving directions for the best route to go from Lexington, Kentucky to Columbia, South Carolina.

Enlarge the route map Lexington, Kentucky - Columbia, South Carolina

Driving directions from Lexington, Kentucky to Columbia, South Carolina

I 75 $south, I 26 $east

432.2 mi6 hours 45 mins

Head northeast on South Broadway (US 27) 500 feet
Turn right onto West Short Street 0.8 mi
Turn left onto Midland Avenue (US 60) 0.4 mi
Continue right onto Winchester Road (US 60) 3.3 mi
Take the ramp 0.2 mi
Merge left onto I 75 S 163.1 mi
Continue onto I 275 S 0.3 mi
Take the ramp towards I 640 East: Asheville 0.2 mi
Merge left onto I 640 E 6.7 mi
Keep left towards I 40 East: Asheville 28.5 mi
Keep right towards I 40 East: Asheville 76.3 mi
Take the ramp towards I 26 East: Hendersonville 13.3 mi
Continue onto I 26 E 134.6 mi
Keep left towards I 126: Columbia 3.4 mi
Take the ramp 0.3 mi
Continue onto Huger Street (US 21) 0.6 mi
Make a U-turn and continue on Huger Street (US 21) 100 feet
You have arrived at your destination, on the left

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Lexington, Kentucky - Columbia, South Carolina

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