Dwight D Eisenhower Highway, I 70 $west
312.9 mi5 hours 13 mins
| Head west on East Wabash Avenue | 600 feet | |
| Turn left onto East Melbourne Avenue | 900 feet | |
| Turn left onto South 3rd Street (SR 25) | 0.4 mi | |
| Continue onto Burlington Avenue (SR 25) | 1.8 mi | |
| Continue onto SR 29 | 30.7 mi | |
| Continue onto US 421 | 17.5 mi | |
| Enter the roundabout and take the 2nd exit onto South Michigan Road (US 421 S) | 100 feet | |
| Exit the roundabout onto South Michigan Road (US 421 S) | 8.5 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto I 465 W | 1.1 mi | |
| Take the ramp towards I 465 South | 0.5 mi | |
| Continue onto I 465 S | 14.9 mi | |
| Take the ramp towards I 70: St. Louis | 0.2 mi | |
| Keep right towards I 70 West: St. Louis | 2.7 mi | |
| Keep left at the fork | 0.3 mi | |
| Merge left onto I 70 | 133.6 mi | |
| Keep right towards I 70 West: Saint Louis | 76.7 mi | |
| Keep left towards I 55: Saint Louis | 16.7 mi | |
| Keep left towards I 55 South: Louisville | 0.7 mi | |
| Merge left onto I 55 S | 1.0 mi | |
| Keep right towards IL 3 South: Cahokia | 1.6 mi | |
| Keep left towards I 64 West | 2.2 mi | |
| Take exit 38A towards Forest Park Avenue | 0.4 mi | |
| Go straight onto Forest Park Avenue | 0.4 mi | |
| Turn right onto South Spring Avenue | 500 feet | |
| Turn left onto Laclede Avenue | 800 feet | |
| You have arrived at your destination, on the right |
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Logansport, IN, USA - St. Louis, MO, USA