US 64; US 87, I 25 $north
545.2 mi8 hours 28 mins
| Head east on Broadway Street | 200 feet | |
| Turn left onto Buddy Holly Avenue | 1.0 mi | |
| Continue onto Municipal Drive | 500 feet | |
| Turn left onto North I-27 | 100 feet | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto Marshall Formby Memorial Highway (I 27 N) | 105.8 mi | |
| Merge left onto Canyon Expressway (I 27 N) | 5.7 mi | |
| Take the ramp towards Loop 335: Hollywood Road | 900 feet | |
| Continue onto Canyon Drive | 700 feet | |
| Turn left onto Hollywood Road (Loop 335) | 1.4 mi | |
| Continue onto South Loop 335 West (Loop 335) | 0.3 mi | |
| Continue onto South Soncy Road (Loop 335) | 8.1 mi | |
| Take the ramp | 0.4 mi | |
| Turn left onto Tascosa Road (RM 1061) | 30.7 mi | |
| Turn right onto US 385 | 27.9 mi | |
| Take the ramp onto US 385 | 1.4 mi | |
| Make a slight right onto US 87 N | 12.1 mi | |
| Continue onto US 87 | 38.0 mi | |
| Continue onto United States Highway 87 (US 87 N) | 11.3 mi | |
| Continue onto US 64 | 79.8 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto I 25 N | 107.9 mi | |
| Take the ramp towards 13th Street | 0.4 mi | |
| Merge left onto I 25 N | 0.6 mi | |
| Continue onto I 25 N | 109.8 mi | |
| Take exit 210A towards US 40 | 0.4 mi | |
| Keep right at the fork | 200 feet | |
| Merge left onto West Colfax Avenue (I 70 Bus) | 1.1 mi | |
| You have arrived at your destination |
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Lubbock, Texas - Denver, Colorado