I 40, I 81 $north
888.8 mi13 hours 22 mins
| Head east on Poplar Avenue | 0.3 mi | |
| Turn left onto North Danny Thomas Boulevard (US 51) | 0.6 mi | |
| Turn right onto North Parkway | 3.1 mi | |
| Turn right onto East Parkway North (US 64) | 0.2 mi | |
| Turn left onto Sam Cooper Boulevard | 6.0 mi | |
| Continue onto I 40 | 194.5 mi | |
| Keep left onto I 40 | 4.1 mi | |
| Keep left towards I 40 East: Knoxville | 0.5 mi | |
| Continue towards I 24 West: Clarksville | 0.5 mi | |
| Keep right towards I 40 East: Knoxville | 2.1 mi | |
| Keep left towards I 40 East: Knoxville | 208.2 mi | |
| Keep left towards I 81 North: Bristol | 296.8 mi | |
| Take the ramp towards I 64 East: Richmond | 90.0 mi | |
| Take the ramp towards I 295 North: Washington | 1.2 mi | |
| Continue onto I 295 | 22.9 mi | |
| Take the ramp towards I 64 East: Norfolk | 1.2 mi | |
| Merge left onto I 64 E | 53.1 mi | |
| Take the ramp towards VA 143 | 0.4 mi | |
| Keep right towards VA 143 East | 0.5 mi | |
| Go straight onto Jefferson Avenue (VA 143) | 2.4 mi | |
| Make a U-turn and continue on Jefferson Avenue (VA 143) | 700 feet | |
| You have arrived at your destination |
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Memphis, Tennessee - Newport News, Virginia