I 20; I 59 $north, I 20
462.4 mi7 hours 26 mins
| Head north on 25th Avenue | 0 feet | |
| Turn right onto 8th Street | 700 feet | |
| Turn right onto 23rd Avenue | 0.2 mi | |
| Turn left onto Front Street | 400 feet | |
| Turn right onto 22nd Avenue | 0.9 mi | |
| Take the ramp on the right towards North I 59: Tuscaloosa | 600 feet | |
| Merge left onto I 20 | 124.7 mi | |
| Take the ramp towards I 459 North: Gadsden | 0.5 mi | |
| Continue onto John M. Harbert III Freeway (I 459 N) | 8.7 mi | |
| Continue onto John M Harbert III Freeway (I 459 N) | 2.0 mi | |
| Continue onto John M. Harbert III Freeway (I 459 N) | 17.8 mi | |
| Take exit 29 towards I 20: Birmingham | 900 feet | |
| Keep right towards I 20 East: Atlanta | 0.6 mi | |
| Merge left onto I 20 | 133.8 mi | |
| Take the ramp towards I 75 North: Chattanooga | 900 feet | |
| Keep left towards I 75 North: Chattanooga | 0.9 mi | |
| Merge left onto Downtown Connector (I 75 N) | 0.7 mi | |
| Continue onto James Wendell George Parkway (I 75 N) | 2.6 mi | |
| Keep left towards I 85 North: Greenville | 28.4 mi | |
| Take the ramp on the left towards I 985 North: Gainesville | 24.3 mi | |
| Continue onto Cornelia Highway (US 23) | 12.8 mi | |
| Continue onto Tommy Irwin Parkway (US 23) | 7.4 mi | |
| Continue onto US 23 N | 1.8 mi | |
| Continue onto US 23 | 6.4 mi | |
| Keep left onto US 23 | 28.8 mi | |
| Continue onto US 23 | 14.7 mi | |
| Take the ramp on the right onto US 23 | 0.5 mi | |
| Continue onto Sylva Road (US 23) | 6.5 mi | |
| Continue onto Sylva Highway (US 23) | 13.1 mi | |
| Take the ramp onto US 23 N | 0.4 mi | |
| Merge left onto Great Smoky Mountains Expressway (US 23 N) | 20.0 mi | |
| Take the ramp towards US 276 South: Waynesville | 900 feet | |
| Make a sharp left onto Russ Avenue (US 276) | 1.5 mi | |
| Turn left onto Dellwood Road (US 19) | 1.8 mi | |
| Turn left onto Swanger Lane | 100 feet | |
| You have arrived at your destination, on the right |
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Meridian, Mississippi - Tupelo's