I 95 $south, I 81 $south
784.3 mi12 hours 38 mins
| Head southwest on Washington Street | 2.5 mi | |
| Continue onto Meriden Road (CT 66) | 4.2 mi | |
| Take exit 10 on the left towards I 91 South: New Haven | 0.3 mi | |
| Merge left onto I 91 S | 19.5 mi | |
| Keep right towards I 95 South: New York City | 700 feet | |
| Keep left towards I 95 South: New York City | 0.5 mi | |
| Merge left onto I 95 S | 63.5 mi | |
| Keep right towards I-95 north: New England | 0.6 mi | |
| Keep right onto I 95 S | 0.7 mi | |
| Continue onto Cross Bronx Expressway Westbound (I-95 Southbound S) | 0.8 mi | |
| Continue onto Cross Bronx Expressway (I 95 S) | 3.8 mi | |
| Continue onto Trans-Manhattan Expressway (I 95 S) | 500 feet | |
| Keep right onto Trans-Manhattan Expressway (I 95 S) | 0.6 mi | |
| Continue onto George Washington Bridge (lower level) (I 95 S) | 1.7 mi | |
| Continue onto New Jersey Turnpike (I 95) | 5.0 mi | |
| Keep left onto New Jersey Turnpike Western Spur ramp (I 95 S) | 10.3 mi | |
| Take the ramp towards I 78: Newark Airport | 1.4 mi | |
| Keep right at the fork | 700 feet | |
| Make a slight right | 700 feet | |
| Merge left onto Interstate 78 Local (I 78 W) | 400 feet | |
| Take the ramp on the left onto I 78 | 200 feet | |
| Merge left onto Interstate 78 Express (I 78 W) | 59.6 mi | |
| Keep left towards Express E-ZPass Only | 0.3 mi | |
| Merge right onto I 78 W | 21.8 mi | |
| Keep left towards I 78 West: Harrisburg | 53.2 mi | |
| Continue towards I 81 South: Harrisburg | 0.7 mi | |
| Merge left onto I 81 S | 446.1 mi | |
| Take the ramp towards I 381: Bristol | 0.8 mi | |
| Continue onto I 381 S | 1.0 mi | |
| Continue onto Commonwealth Avenue | 1.2 mi | |
| Continue onto Volunteer Parkway (US 11E) | 6.8 mi | |
| Continue onto Bristol Highway (US 11E) | 13.9 mi | |
| Turn left onto North Roan Street (US 11E) | 0.8 mi | |
| Take the ramp onto US 19W S | 23.3 mi | |
| Continue onto I 26 E | 20.7 mi | |
| Continue onto I 26 Future E | 15.9 mi | |
| Take the ramp towards NC 251: University of North Carolina Asheville | 0.3 mi | |
| Turn left onto Broadway Street (NC 251) | 1.7 mi | |
| Continue onto North Lexington Avenue | 400 feet | |
| Turn left onto Woodfin Street | 300 feet | |
| Turn left onto Broadway Street (US 25) | 200 feet | |
| You have arrived at your destination |
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Middletown, Connecticut - Asheville, North Carolina