I 64 $west, US 35 $west
512.8 mi8 hours 18 mins
| Head west on Midlothian Turnpike (US 60) | 1.7 mi | |
| Take the ramp on the right | 1.0 mi | |
| Merge left onto World War II Veterans Memorial Highway (VA 288 N) | 10.9 mi | |
| Keep left at the fork | 0.8 mi | |
| Merge left onto I 64 W | 86.8 mi | |
| Keep left towards I 64 West: Lexington | 30.5 mi | |
| Take the ramp towards I 64 West: Lexington | 120.7 mi | |
| Keep right onto I 64 W | 0.4 mi | |
| Merge left onto West Virginia Turnpike (I 64 W) | 61.0 mi | |
| Keep left towards I 64 West: Huntington | 17.8 mi | |
| Take the ramp towards US 35: Winfield | 0.5 mi | |
| Keep left towards Scott Depot | 700 feet | |
| Turn right onto US 35 N | 14.1 mi | |
| Continue onto US 35 | 12.2 mi | |
| Continue onto US 35 N | 9.9 mi | |
| Continue onto US 35 W | 61.4 mi | |
| Keep left towards US 35 West: Dayton | 39.9 mi | |
| Take exit 72 towards SR 435: Columbus | 0.3 mi | |
| Turn left onto Old United States Highway 35 (SR 435) | 0.9 mi | |
| Turn left towards I 71 South: Cincinnati | 0.3 mi | |
| Merge left onto I 71 S | 28.7 mi | |
| Continue onto I 71 W | 3.5 mi | |
| Continue onto I 71 S | 7.2 mi | |
| Take exit 25 towards SR 741 North: Kings Mills Road | 0.3 mi | |
| Turn right onto Kings Mills Road (SR 741) | 0.8 mi | |
| Turn left to stay on Kings Mills Road | 1.1 mi | |
| You have arrived at your destination |
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Midlothian, Virginia - Mason, Ohio