US 84, US 67
359.1 mi6 hours 40 mins
| Head northwest on West Avenue D | 200 feet | |
| Turn right onto West 6th Street | 0.2 mi | |
| Turn right onto West American Boulevard (US 70) | 62.1 mi | |
| Keep right at the fork | 0.9 mi | |
| Continue onto Clovis Road (US 84) | 5.2 mi | |
| Make a slight right onto Avenue Q (US 84) | 700 feet | |
| Turn left onto Marsha Sharp Freeway Frontage Road | 0.9 mi | |
| Turn right onto I-27 | 300 feet | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto Marshall Formby Memorial Highway (I 27 S) | 4.3 mi | |
| Continue onto Tahoka Highway (US 87 S) | 4.5 mi | |
| Continue onto Highway 87 (US 87 S) | 51.3 mi | |
| Continue onto Lubbock Highway (US 87 S) | 1.1 mi | |
| Continue onto North Lynn Avenue (US 87) | 0.5 mi | |
| Turn right onto North 4th Street (US 180) | 0.7 mi | |
| Turn left onto North Bryan Avenue (TX 137) | 2.5 mi | |
| Keep right onto TX 349 | 49.3 mi | |
| Turn right onto West Loop 250 North | 700 feet | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto Loop 250 W | 9.4 mi | |
| Turn right onto Interstate 20 West Frontage Road (TX 349) | 600 feet | |
| Take the ramp on the left | 0.4 mi | |
| Merge left onto I 20 | 27.3 mi | |
| Keep left onto I 20 | 23.8 mi | |
| Take the ramp towards SH 18: Kermit | 0.3 mi | |
| Turn left onto South Stockton Avenue (TX 18) | 16.0 mi | |
| Continue onto D Avenue (TX 18) | 31.7 mi | |
| Turn right onto Northwest 10 Frontage Road | 600 feet | |
| Take the ramp | 0.2 mi | |
| Merge left onto I 10 | 9.8 mi | |
| Take the ramp towards US 67 south: Alpine | 0.3 mi | |
| Turn left onto US 67 | 55.5 mi | |
| Turn right onto North 5th Street (TX 118) | 700 feet | |
| Turn left onto West Lockhart Avenue | 500 feet | |
| You have arrived at your destination, on the right |
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Muleshoe, TX - Alpine, TX