Milwaukee - Muskegon, New York State Thruway
991.5 mi17 hours 5 mins
| Head southwest on South Commercial Street (WI 114) | 0.3 mi | |
| Turn right onto Winneconne Avenue (WI 114) | 1.0 mi | |
| Enter the roundabout and take the 2nd exit onto Winneconne Avenue (WI 114) | 100 feet | |
| Exit the roundabout onto Winneconne Avenue (WI 114) | 300 feet | |
| Enter the roundabout and take the 2nd exit onto Winneconne Avenue (WI 114) | 100 feet | |
| Exit the roundabout onto Winneconne Avenue (WI 114) | 0.2 mi | |
| Turn left | 0.3 mi | |
| Merge left onto I 41 | 83.1 mi | |
| Take exit 47A towards WI 175: Appleton Avenue | 0.3 mi | |
| Merge right onto West Appleton Avenue (WI 175) | 6.8 mi | |
| Make a slight right onto Stadium Freeway (WI 175) | 1.7 mi | |
| Take exit 38A on the left towards I 94 East: Downtown | 0.4 mi | |
| Merge right onto East-West Freeway (I 94 E) | 1.9 mi | |
| Take exit 310C on the left towards I 794 East: Lakefront | 900 feet | |
| Keep left towards I 794 East: Lakefront | 1.0 mi | |
| Continue towards Lakefront | 2.0 mi | |
| Take the ramp towards Port of Milwaukee | 0.5 mi | |
| Turn left onto South Carferry Drive | 0.3 mi | |
| Keep left at the fork | 200 feet | |
| Turn left onto South Lincoln Memorial Drive | 200 feet | |
| Turn right | 600 feet | |
| Turn left | 400 feet | |
| Make a slight right | 400 feet | |
| Turn right | 200 feet | |
| Take the ferry Milwaukee - Muskegon | 83.0 mi | |
| Continue straight onto Estes Street | 100 feet | |
| Turn right to stay on Estes Street | 0.3 mi | |
| Turn left onto Lake Shore Drive | 0.4 mi | |
| Continue onto West Laketon Avenue | 1.1 mi | |
| Turn right onto Seaway Drive (US-31BR) | 49.9 mi | |
| Continue onto I 96 E | 43.9 mi | |
| Take exit 89 towards I 69 East: Flint | 2.5 mi | |
| Merge left onto I 69 E | 122.6 mi | |
| Continue onto CBSA - Sarnia (Point Edward) Point Of Entry Traveler Lanes (402 E) | 63.9 mi | |
| Merge left onto Highway 401 (401 E) | 31.1 mi | |
| Keep right towards 403: Brantford | 39.9 mi | |
| Take the ramp towards Lincoln M. Alexander Parkway | 0.7 mi | |
| Continue onto Lincoln M. Alexander Parkway | 6.2 mi | |
| Continue onto Red Hill Valley Parkway | 5.3 mi | |
| Keep right towards QEW: Niagara | 1.2 mi | |
| Merge left onto Queen Elizabeth Way (QEW S) | 30.8 mi | |
| Keep left towards 405: Queenston | 5.8 mi | |
| Continue onto Queenston–Lewiston Bridge (405) | 800 feet | |
| Continue onto Lewiston-Queenston Bridge (I 190) | 14.7 mi | |
| Take exit 16 towards I 290 East: Tonawanda | 0.4 mi | |
| Continue onto Youngmann Expressway (I 290 E) | 9.4 mi | |
| Keep left towards I 90 East: Albany | 0.6 mi | |
| Merge left onto New York State Thruway (I 90 E) | 285.1 mi | |
| Take exit 21A towards Massachusetts Turnpike | 0.4 mi | |
| Continue straight | 0.7 mi | |
| Continue onto New York State Thruway Berkshire Connector | 17.3 mi | |
| Merge left onto New York State Thruway Berkshire Connector (I 90 E) | 6.6 mi | |
| Continue onto Massachusetts Turnpike (I 90 E) | 62.3 mi | |
| Take exit 8 towards MA 32: Palmer | 0.6 mi | |
| Turn right onto Thorndike Street (MA 32) | 0.7 mi | |
| Turn left onto Park Street (US 20) | 2.8 mi | |
| Continue onto Boston Road East (US 20) | 0.4 mi | |
| Continue onto Palmer Road (US 20) | 400 feet | |
| You have arrived at your destination |
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Neenah, Wisconsin - Fentonville, Massachusetts