I 41; US 41, I 65 $south
883.5 mi14 hours 27 mins
| Head east on West Wolf River Avenue (CTH X) | 900 feet | |
| Turn right onto Division Street (CTH X) | 900 feet | |
| Turn left onto East Beacon Avenue (US 45 Business) | 900 feet | |
| Turn right onto Mill Street (US 45 Business) | 1.2 mi | |
| Take the ramp on the right | 400 feet | |
| Merge left onto US Highway 45 (US 45) | 7.1 mi | |
| Enter the roundabout and take the 2nd exit towards US 45 South: Oshkosh | 100 feet | |
| Exit the roundabout towards US 45 South: Oshkosh | 2.4 mi | |
| Keep left towards US 10 East: Appleton | 1.0 mi | |
| Merge left onto Vietnam War Veterans Memorial Highway (US 10 E) | 2.5 mi | |
| Keep right towards US 45 South: Oshkosh | 12.4 mi | |
| Take the ramp on the left towards I 41 South: Milwaukee | 1.1 mi | |
| Merge left onto I 41 | 86.1 mi | |
| Continue onto Airport Freeway (I 41) | 4.2 mi | |
| Take exit 10B on the left towards I 41 South: Chicago | 1.1 mi | |
| Keep left towards I 41 South: Chicago | 700 feet | |
| Merge left onto North-South Freeway (I 41) | 32.1 mi | |
| Continue onto I 41 S | 0.7 mi | |
| Keep right towards Chicago | 24.4 mi | |
| Keep left towards I 94 East Toll: Chicago | 1.0 mi | |
| Keep left onto Edens Spur (I 94 E) | 3.8 mi | |
| Continue onto Edens Expressway (I 94 E) | 13.2 mi | |
| Keep right onto Edens Expressway (I 94 E) | 0.6 mi | |
| Merge left onto Kennedy Expressway (I 90) | 8.1 mi | |
| Continue onto Dan Ryan Expressway (I 90) | 2.4 mi | |
| Keep left towards I 90 Express | 3.8 mi | |
| Take the ramp towards I 90 East: Chicago Skyway | 0.4 mi | |
| Merge right onto Dan Ryan Expressway (I 90) | 0.5 mi | |
| Keep left towards I 90 East: Chicago Skyway | 10.6 mi | |
| Keep left onto Indiana Toll Road (I 90) | 11.3 mi | |
| Take the ramp towards IN 53 | 0.3 mi | |
| Turn right onto Broadway (SR 53) | 0.2 mi | |
| Turn left onto East 5th Avenue (US 12) | 1.6 mi | |
| Turn right onto I 65 S | 132.7 mi | |
| Keep left onto I 65 S | 299.6 mi | |
| Keep left towards I 24 East: Nashville | 2.4 mi | |
| Keep left towards I 24 East: Chattanooga | 2.8 mi | |
| Keep right towards I 40 West: Memphis | 0.4 mi | |
| Merge left onto I 40 | 0.6 mi | |
| Keep left towards I 65 South: Huntsville | 0.4 mi | |
| Merge right onto I 65 S | 28.8 mi | |
| Keep left onto I-65 (I 65 S) | 66.1 mi | |
| Continue onto I 65 (I 65 S) | 0.2 mi | |
| Continue onto I-65 (I 65 S) | 93.0 mi | |
| Take the ramp towards I 20 West: Tuscaloosa | 0.4 mi | |
| Merge left onto I 20 | 14.2 mi | |
| Take the ramp towards Alabama Adventure Parkway | 0.2 mi | |
| Turn right onto Vision Land Parkway | 1.4 mi | |
| Turn right onto Powder Plant Road (CR 47) | 0.5 mi | |
| Turn left onto Johns Road (CR 36) | 5.0 mi | |
| Turn left to stay on Johns Road (CR 36) | 100 feet | |
| You have arrived at your destination |
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New London, Wisconsin - Adger, Alabama