How to get from O'fallon, MO, USA to Lancaster, PA, USA

Discover, print or download the driving directions for the best route to go from O'fallon, MO, USA to Lancaster, PA, USA.

Enlarge the route map O'fallon, MO, USA - Lancaster, PA, USA

Driving directions from O'fallon, MO, USA to Lancaster, PA, USA

I 70, Pennsylvania Turnpike

847.4 mi13 hours 9 mins

Head east on Prince David Drive 0.2 mi
Turn right onto Saint Matthew Avenue 600 feet
Turn left onto Prince Ruppert Drive 200 feet
Turn right onto Westoff Park 900 feet
Turn left to stay on Westoff Park 0.3 mi
Turn right onto TR Hughes Boulevard 0.8 mi
Take the ramp on the left 0.2 mi
Merge left onto I 70 E 4.2 mi
Keep right towards MO 370 East 13.0 mi
Continue onto I 270 E 27.7 mi
Merge right towards I 70 East: Indianapolis 82.7 mi
Keep right towards I 70 East: Indianapolis 139.9 mi
Keep right towards 10 Street 120.2 mi
Keep left onto I 70 49.1 mi
Keep right onto West Freeway (I 70) 3.2 mi
Continue onto South Innerbelt (I 70) 2.0 mi
Continue onto East Freeway (I 70) 118.3 mi
Keep right onto I 470 E 10.8 mi
Merge left onto I 70 55.4 mi
Take the ramp towards PA 51 South: Uniontown 0.2 mi
Merge left onto PA 51 S 800 feet
Turn left onto PA 981 2.0 mi
Turn left onto 2nd Street (PA 981) 0.2 mi
Turn left onto Dutch Hollow Road 0.9 mi
Continue onto Race Track Road 900 feet
Turn right onto Motor Drome Road 1.0 mi
Continue onto Turkeytown Road 0.9 mi
Turn right onto Mount Pleasant Road (PA 31) 1.7 mi
Take the ramp on the left 700 feet
Merge left onto I 70 6.0 mi
Take exit 58 towards I 70 Toll East: Harrisburg 0.5 mi
Keep left towards I 70 East: Harrisburg 0.4 mi
Merge left onto Pennsylvania Turnpike (I 70 E) 172.9 mi
Take the ramp towards I 283: Harrisburg 0.5 mi
Continue onto I 283 N 400 feet
Take the ramp towards PA 283 East: Airport 0.3 mi
Merge left onto PA 283 E 28.2 mi
Take the ramp towards Fruitville Pike 0.2 mi
Continue onto Chester Road 0.3 mi
Turn right onto Fruitville Pike 0.9 mi
Continue onto North Prince Street (PA 72) 1.3 mi
Turn left onto West King Street (PA 462) 0.2 mi
You have arrived at your destination

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O'fallon, MO, USA - Lancaster, PA, USA

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