I 22 $east; US 78 $east, I 75 $south
1,227.1 mi18 hours 59 mins
| Head east on Northwest 4th Street | 0.5 mi | |
| Turn left onto Harrison Avenue | 600 feet | |
| Make a slight right onto Northeast 5th Street | 400 feet | |
| Take the ramp | 100 feet | |
| Keep right towards I 235 South | 900 feet | |
| Merge left onto Centennial Expressway (I 235 S) | 0.7 mi | |
| Take the ramp on the left towards I 35 North: Wichita | 0.3 mi | |
| Merge right onto Crosstown Expressway (I 40 E) | 1.2 mi | |
| Keep left towards I 240 East: Fort Smith | 11.8 mi | |
| Continue onto Vietnam Veteran's Memorial Highway (I 40 E) | 75.4 mi | |
| Continue towards I 40 East: Fort Smith | 1.4 mi | |
| Continue onto Vietnam Veteran's Memorial Highway (I 40 E) | 243.6 mi | |
| Keep right onto I 40 | 124.9 mi | |
| Take the ramp towards I 55 South: Memphis | 0.5 mi | |
| Keep left onto I 55 E | 1.2 mi | |
| Continue onto I 55 | 3.5 mi | |
| Take the ramp towards I 55 South: Jackson Mississippi | 6.5 mi | |
| Continue onto I 240 E | 3.2 mi | |
| Take the ramp towards US 78: Birmingham | 700 feet | |
| Keep right towards US 78 East: Birmingham | 0.3 mi | |
| Merge left onto Lamar Avenue (US 78) | 221.0 mi | |
| Keep right towards I 65 South: Birmingham | 0.5 mi | |
| Merge left onto I 65 S | 2.0 mi | |
| Take the ramp towards Finley Boulevard | 1,000 feet | |
| Turn left onto Finley Boulevard (SR 378) | 0.7 mi | |
| Turn right onto Carraway Boulevard (US 31) | 1.5 mi | |
| Continue onto Red Mountain Expressway (US 31 S) | 2.9 mi | |
| Take the ramp onto US 280 | 108.9 mi | |
| Take the ramp on the left onto US 280 | 3.2 mi | |
| Take the ramp towards US 280: Opelika | 0.2 mi | |
| Keep right onto US 280 | 300 feet | |
| Merge left onto Columbus Parkway (US 280) | 21.1 mi | |
| Continue onto US 280 | 6.0 mi | |
| Continue onto Victory Drive (US 27) | 7.4 mi | |
| Continue onto US 27 S | 7.4 mi | |
| Continue onto US 27 | 1.5 mi | |
| Continue onto US 280 E | 18.7 mi | |
| Continue onto Wall Street (GA 520) | 16.1 mi | |
| Continue onto North Parrott Street (GA 520) | 1.0 mi | |
| Continue onto Columbus Highway (GA 520) | 7.9 mi | |
| Continue onto Martin Luther King Jr Drive (GA 45) | 0.5 mi | |
| Continue onto Roundtree Drive (GA 45) | 0.2 mi | |
| Continue onto Vine Street Northwest (GA 45) | 0.3 mi | |
| Continue onto Roundtree Drive Southwest (GA 45) | 400 feet | |
| Continue onto Rountree Drive Southwest (GA 45) | 0.5 mi | |
| Continue onto Forrester Drive Southeast (US 82) | 1.1 mi | |
| Continue onto Albany Highway (US 82) | 5.4 mi | |
| Go straight onto Highway Street (US 82) | 1.0 mi | |
| Continue onto Albany Highway (US 82) | 7.6 mi | |
| Continue onto Warrington Road (US 82) | 1.2 mi | |
| Keep right onto Liberty Expressway (US 82 E) | 8.1 mi | |
| Take exit 3 towards US 82 East: Sylvester | 0.4 mi | |
| Turn left onto Clark Avenue (US 82) | 5.4 mi | |
| Merge left onto Sylvester Highway (US 82) | 14.9 mi | |
| Continue onto US 82 | 17.0 mi | |
| Take the ramp | 0.4 mi | |
| Merge left onto I 75 S | 205.3 mi | |
| Keep left towards South Turnpike | 42.1 mi | |
| Keep left onto Florida's Turnpike | 6.9 mi | |
| Take the ramp towards I 4: Downtown Orlando | 0.8 mi | |
| Continue straight | 0.3 mi | |
| Continue onto I-14 | 0.5 mi | |
| Take exit 78 towards Conroy Road | 0.6 mi | |
| Turn right onto Conroy Road | 1.1 mi | |
| Turn right onto John Young Parkway (CR 423) | 1.0 mi | |
| Turn right onto Oak Ridge Road | 0.5 mi | |
| Turn left onto Bonnie Brook Boulevard | 600 feet | |
| You have arrived at your destination |
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Oklahoma City, Oklahoma - Oak Ridge, Florida