I 44 $east; US 50 $east, I 44 $east
56.9 mi1 hour 3 mins
| Head north on North 1st Street (MO F) | 100 feet | |
| Turn right onto East Osage Street (I 44 Business) | 1.4 mi | |
| Continue onto Historic Route 66 (I 44 Business) | 2.9 mi | |
| Make a sharp left onto Allenton Six Flags Road (I 44 Business) | 300 feet | |
| Take the ramp on the right | 0.2 mi | |
| Merge left onto I 44 E | 29.4 mi | |
| Keep right towards I 55 North | 0.8 mi | |
| Keep right towards IL 3 South: East Saint Louis | 1.2 mi | |
| Merge left onto I 55 N | 0.9 mi | |
| Continue onto I 55 N | 700 feet | |
| Keep left towards I 55 North: Chicago | 0.6 mi | |
| Merge right onto I 55 N | 11.5 mi | |
| Take the ramp towards IL 159 North: Maryville | 0.2 mi | |
| Make a slight right onto South Center Street (IL 159) | 200 feet | |
| Continue onto S Center Street (IL 159) | 0.3 mi | |
| Continue onto Maryville Road (IL 159) | 0.5 mi | |
| Continue onto South Center Street (IL 159) | 1.3 mi | |
| Continue onto South State RT 159 (IL 159) | 2.9 mi | |
| Turn left onto Illini Drive (IL 159) | 0.3 mi | |
| Continue onto Plum Street (IL 159) | 1.7 mi | |
| Continue onto South Main Street (IL 159) | 0.5 mi | |
| Turn right onto Hillsboro Avenue | 400 feet | |
| You have arrived at your destination |
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Pacific, Missouri - Edwardsville, Illinois